Results 21 to 30 of about 2,231 (116)
Influence of the Season and Region Factor on Phosphoproteome of Stallion Epididymal Sperm
Animals, 2021 Epididymal maturation can be defined as a scope of changes occurring during epididymal transit that prepare spermatozoa to undergo capacitation. One of the most common post-translational modifications involved in the sperm maturation process and their ...
Katarzyna Dyrda +3 more
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Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins.
PLoS ONE, 2013 Nesprin-1 and nesprin-2 are nuclear envelope (NE) proteins characterized by a common structure of an SR (spectrin repeat) rod domain and a C-terminal transmembrane KASH [Klarsicht-ANC-Syne-homology] domain and display N-terminal actin-binding CH ...
Flavia Autore +6 more
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Cytoskeletal Protein Variants Driving Atrial Fibrillation: Potential Mechanisms of Action
Cells, 2022 The most common clinical tachyarrhythmia, atrial fibrillation (AF), is present in 1–2% of the population. Although common risk factors, including hypertension, diabetes, and obesity, frequently underlie AF onset, it has been recognized that in 15% of the
Stan W. van Wijk +4 more
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Cells, 2022 Mutations in genes encoding proteins associated with the linker of nucleoskeleton and cytoskeleton (LINC) complex within the nuclear envelope cause different diseases with varying phenotypes including skeletal muscle, cardiac, metabolic, or nervous ...
Emily C. Storey, Heidi R. Fuller
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The Drosophila melanogaster attP40 docking site and derivatives are insertion mutations of msp-300.
PLoS ONE, 2022 The ɸC31 integrase system is widely used in Drosophila melanogaster to allow transgene targeting to specific loci. Over the years, flies bearing any of more than 100 attP docking sites have been constructed.
Kevin van der Graaf +4 more
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eLife, 2023 Endothelial cells line all blood vessels, where they coordinate blood vessel formation and the blood-tissue barrier via regulation of cell-cell junctions.
Danielle B Buglak +16 more
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Annals of Indian Academy of Neurology, 2020 A 24-year-old female presented with wasting and weakness of both hands and fasciculations over the chin since 12 years, followed by imbalance while walking and speech changes since 10 years. Her 12-year-old sister also had a similar clinical presentation.
Swaleha Nurulla Nadaf +3 more
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Involvement of Actin and Actin-Binding Proteins in Carcinogenesis
Cells, 2020 The actin cytoskeleton plays a crucial role in many cellular processes while its reorganization is important in maintaining cell homeostasis. However, in the case of cancer cells, actin and ABPs (actin-binding proteins) are involved in all stages of ...
Magdalena Izdebska +3 more
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Bioengineering, 2021 Vascular smooth muscle cells (VSMCs) remodel vascular walls actively owing to mechanical cues and dedifferentiate to the synthetic phenotype from contractile phenotype in pathological conditions.
Kazuaki Nagayama
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Nuclear Envelope Transmembrane Proteins in Myotonic Dystrophy Type 1
Frontiers in Physiology, 2018 Myotonic dystrophy type 1 (DM1) is a multisystemic disorder with predominant myotonia and muscular dystrophy which is caused by CTG-repeat expansions in the DMPK gene. These repeat expansions are transcribed and the resulting mRNA accumulates RNA-binding
Stefan Hintze +4 more
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