Results 51 to 60 of about 49,900 (269)
Advanced Science, EarlyView.This work presents a CRISPR‐based, ultrasensitive multiplex protein detection array capable of simultaneously analyzing six plasma biomarkers associated with Alzheimer's disease (AD). By integrating antibody‐mediated signal transduction, recombinase polymerase amplification, and spatially encoded CRISPR‐Cas12a, the system achieves detection sensitivity
Liding Zhang +9 more
wiley +1 more source
Arquivos do Instituto Biológico, 2018 : Equine granulocytic anaplasmosis is caused by Anaplasma phagocytophilum, a gram negative, obligatory intracellular bacterium, member of Anaplasmataceae family, included in the Rickettsiales order.
Luan Gavião Prado +7 more
doaj +1 more source
Detection of streptococcal pyrogenic exotoxin genes by a nested polymerase chain reaction
Molecular and Cellular Probes, 1993 Severe invasive disease associated with group A Streptococcus (GAS) has recently increased in frequency. Isolates of GAS from normally sterile sites were examined for the streptococcal pyrogenic exotoxin genes spe A, spe B and spe C to determine if they play a role in this disease.
C M, Black +5 more
openaire +2 more sources
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
Periodontal diseases and adverse pregnancy outcomes. Present and future
Periodontology 2000, EarlyView., 2023 Abstract For more than two decades the possible association between periodontal diseases and adverse pregnancy outcomes has been extensively evaluated. Numerous observational, intervention, and mechanistic studies have offered valuable information on this topic.
Yiorgos A. Bobetsis +3 more
wiley +1 more source
Trypanosoma brucei gambiense in domestic livestock of Kogo and Mbini foci (Equatorial Guinea).
, 2009 OBJECTIVE: To evaluate Trypanosoma brucei gambiense infection in peri-domestic livestock from Kogo and Mbini foci (Equatorial Guinea) in order to investigate its possible implication in the sleeping sickness transmission cycle in these hypoendemic foci ...
Berzosa, P +7 more
core +1 more source
Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction
Advanced Science, EarlyView.This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng +12 more
wiley +1 more source
Nested polymerase chain reaction for diagnostic and genotyping of chlamydia
Technology audit and production reserves, 2012 The article describes the method of determination of chlamydial DNA, worked out by the author, based on nested PCR, and method of results verification by means of additional amplification of chlamydial cryptic plasmid DNA fragment. It is shown that application of nested PCR gives an opportunity to conduct genotyping of chlamydia investigating clinical ...
openaire +4 more sources
Emerging Infectious Diseases, 2005 We developed a sensitive and rapid real-time reverse transcription-polymerase chain reaction (RT-PCR) assay to detect influenza A H5N1 virus in clinical samples.
Enders K.O. Ng +4 more
doaj +1 more source
Applied Food Biotechnology, 2023 Background and Objective: Meat can be contaminated by Leptospira species. This bacterial pathogen causes severe leptospirosis disease in humans and animals.
Ali Hokmi +4 more
doaj +1 more source