Results 91 to 100 of about 16,143 (202)
DataSheet_2_ROS and DNA repair in spontaneous versus agonist-induced NETosis: Context matters.pdf
, 2022 Reactive oxygen species (ROS) is essential for neutrophil extracellular trap formation (NETosis). Nevertheless, how ROS induces NETosis at baseline and during neutrophil activation is unknown. Although neutrophils carry DNA transcription, replication and
Dhia Azzouz (14072781) +1 more
core +1 more source
International Journal of NanomedicineLingping Tan,1,2,* Chi Zhang,1,2,* Xiaoxing Kou,1– 3 Lu Zhao,4 Di Wu,1– 3 Jinyu Li,1,2 Chuanying Yu,1,2 Tansi Xu,1,2 Li Gao,1,2 Xueli Mao,1– 3 Chuanjiang Zhao1,2 1Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University ...
Tan L +10 more
doaj
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Nanobodies for NETosis Tracking and Visualization
Neutrophil extracellular traps (NETs) are pivotal in the immune response, trapping and neutralizing pathogens. The process of NET formation, or NETosis, is a critical innate immune response mechanism implicated in diverse physiological and pathological ...
Peng, Yuli +3 more
core +1 more source
Immunology, EarlyView.The roles of distinct lung neutrophil compartments involved in hvKp infection remain poorly understood. Here, utilising single‐cell RNA sequencing, we identified four neutrophil subsets in the lungs of hvKp‐infected mice: N1, N2, N3a, and N3b, which were organised along a maturation trajectory.
Xiang Fang +7 more
wiley +1 more source
Scientific Reports, 2017 Neutrophils cast neutrophil extracellular traps (NETs) to ensnare microbial pathogens. Nevertheless, the molecular rheostats that regulate NETosis in response to bacteria are not clearly established.
Meraj A. Khan +6 more
doaj +1 more source
Pathogenesis of hidradenitis suppurativa: From susceptibility to chronicity
Journal of the European Academy of Dermatology and Venereology, EarlyView.This review describes hidradenitis suppurativa as a heterogeneous disorder in which genetic susceptibility, epithelial dysfunction, environmental exposures, immune activation and microbial ecology converge differently across patients and disease stages.
Kelsey R. van Straalen +5 more
wiley +1 more source
, 2017 Autoimmune and autoinflammatory diseases have dramatically increased in both developed and developing countries. The etiology of these diseases is complex and developed due to multifactorial causes.
Neslihan Sürsal +3 more
core +1 more source
Besnoitia besnoiti bradyzoite stages induce suicidal- and rapid vital-NETosis
, 2020 International audienceBesnoitia besnoiti is an obligate intracellular apicomplexan protozoan parasite, which causes bovine besnoitiosis. Recently increased emergence within Europe was responsible for significant economic losses in the cattle industry due
Zhou, Ershun +10 more
core +1 more source
napari‐lattice: A user‐friendly image processing tool for lattice light‐sheet microscopy data
Journal of Microscopy, EarlyView.Abstract Lattice light‐sheet microscopy (LLSM) has revolutionised live‐cell imaging with its ability to resolve sub‐cellular detail with high spatiotemporal resolution and minimal phototoxicity. However, LLSM often generates large terabyte‐scale datasets that require complex preprocessing, creating bottlenecks in storage, data handling and analysis ...
Pradeep Rajasekhar +9 more
wiley +1 more source