Results 71 to 80 of about 12,736 (166)

Apoptotic Vesicles Attenuate Acute Lung Injury via CD73-Mediated Inhibition of Platelet Activation and NETosis

open access: yesInternational Journal of Nanomedicine
Lingping Tan,1,2,* Chi Zhang,1,2,* Xiaoxing Kou,1– 3 Lu Zhao,4 Di Wu,1– 3 Jinyu Li,1,2 Chuanying Yu,1,2 Tansi Xu,1,2 Li Gao,1,2 Xueli Mao,1– 3 Chuanjiang Zhao1,2 1Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University ...
Tan L   +10 more
doaj  

Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model

open access: yesMolecular Medicine
Following cerebral ischemia, neutrophil extracellular traps (NETs) contribute significantly to brain damage by exacerbating delayed immune cell infiltration and vascular injury. They are detected both in brain tissue and within blood vessels.
Sang-A. Oh   +4 more
doaj   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez   +6 more
wiley   +1 more source

Case Report: Anti-platelet factor 4 -mediated immunothrombosis in a patient with ANCA vasculitis – a shared mechanism of NETosis

open access: yesFrontiers in Immunology
Anti-platelet factor 4 (PF4) immunothrombosis is characterized by thrombocytopenia, thrombosis and enhanced NETosis and has been described in the absence of prior heparin exposure.
Lital Remez-Gabay   +8 more
doaj   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens   +8 more
wiley   +1 more source

Understanding exosomes in diabetic wound healing

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad   +4 more
wiley   +1 more source

Sepsis Induces a Dysregulated Neutrophil Phenotype That Is Associated with Increased Mortality

open access: yesMediators of Inflammation, 2018
Background. Neutrophil dysfunction in sepsis has been implicated in the pathogenesis of multiorgan failure; however, the role of neutrophil extracellular traps (NETs) remains uncertain.
Jaimin M. Patel   +6 more
doaj   +1 more source

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An   +4 more
wiley   +1 more source

Auto-amplification and spatial propagation of neutrophil extracellular traps

open access: yesCommunications Biology
The release of cellular DNA as neutrophil extracellular traps (NETs) plays a pivotal role in the immune response to pathogens by physically entrapping and killing microbes.
Pan Deng   +5 more
doaj   +1 more source

Feature of NETosis in Chronic Granulomatous Disease and Its Impact on Renal Disorder

open access: yesFrontiers in Bioscience-Landmark
Chronic granulomatous disease (CGD) is an inherited immunodeficiency characterized by impaired phagocytic cells due to mutations in genes encoding the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme complex, leading to recurrent severe
Tetsuya Abe   +7 more
doaj   +1 more source

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