Results 191 to 200 of about 4,546,897 (298)

Pharmacovigilance profiles of three generations of mineralocorticoid receptor antagonists and network toxicology analysis. [PDF]

Front Med (Lausanne)
Lin HH, Cui WH, Xu F, He JY, Li LC, Xu JJ, Jiang X, Mao KL.   +7 more
europepmc   +1 more source

A university‐certified course on dossier assessment for regulatory scientists in Africa—Reporting on our 5‐year experience

British Journal of Clinical Pharmacology, EarlyView.
Aim The shortage of trained clinical assessors in African National Regulatory Authorities (NRAs) poses a challenge to effective regulatory decision‐making. Developed in line with the World Health Organization's (WHO) Global Competency Framework (WHO‐GCF), a university‐certified short course, Dossier assessment for clinical assessors in Africa, was ...
Stephanie Leigh, Boitumelo Semete‐Makokotlela, Ivana Škrnjug‐Yudov, David Mukanga, Delese Mimi Darko, Eric Karikari‐Boateng, Peter Stonier, Luther Gwaza, Precious Matsoso, Bernd Rosenkranz, Birka Lehmann, Arnold G. Vulto, John G. Woodland, Shabir Banoo, Frieda Shigwedha, Maphutheho Selikane, Unathi Mabona‐Mgoqi, Asare Yeboah, Ntombi Mthembu, Goonaseelan ( Colin) Pillai   +19 more
wiley   +1 more source

Integrating network toxicology and in vitro validation to elucidate PET microplastic-induced osteoarthritis pathogenesis. [PDF]

Front Pharmacol
Li Z, Wang L, Huang H, Lu D, Han T, Zhao J, Du G.   +6 more
europepmc   +1 more source

Small animal toxicology /

Diagnose and determine treatment for toxic exposures in small animals with this quick reference! Small Animal Toxicology, 3rd Edition covers hundreds of potentially toxic substances, providing the information you need to manage emergency treatment and ...
Peterson, Michael E.(Michael Edward),Small animal toxicology., Peterson, Michael E.(Michael Edward),, Talcott, Patricia A.   +2 more
core  

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, EarlyView.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

Machine learning-integrated network toxicology uncovers glioma targets of DEHP. [PDF]

Front Toxicol
Li R, Ren C, He L, Wang S, Guo G.
europepmc   +1 more source

Environmental impact of antidepressants: Is a new prescription framework possible?

British Journal of Clinical Pharmacology, EarlyView.
Aims Antidepressants such as venlafaxine and sertraline pose high risks to water ecosystems. As depressive disorders and other mental health conditions become increasingly prevalent worldwide, prescription and environmental presence of these pharmaceuticals continue to rise. This study explores the practical viability of a new framework for prescribing
Matilde Bianconi, Valentina Giunchi, Michael Thiede, Elisa Sangiorgi, Marco Menchetti, Elisabetta Poluzzi   +5 more
wiley   +1 more source

Network Toxicology Reveals the Mechanisms of the Plasticizer Metabolite MECPP in Metabolic Diseases. [PDF]

Int J Mol Sci
Qiu J, Cheng C, Jiang B, Yang D, Peng H.
europepmc   +1 more source

Developing a Laboratory Response Network for Toxicology

Forensic Science International: Synergy, 2019
openaire   +1 more source

Capacity building in medicines development and regulation in Africa—Overview on recent progress

British Journal of Clinical Pharmacology, EarlyView.
Aims Despite advances in health research and digital innovation, many African countries continue to face substantial resource constraints, fragmented capacity‐building efforts and a shortage of skilled professionals in medicines development and regulatory science.
Tirhani Maluleke, Emile Malan, Michael Reid, Patrick Bouic, Haylene Nell, Goonaseelan Pillai, Catriona Waitt, Bernd Rosenkranz   +7 more
wiley   +1 more source