Results 111 to 120 of about 16,068 (197)
Canine Genetics and Epidemiology, 2019 Background N-glycolylneuraminic acid (Neu5Gc) is synthesized from its precursor N-acetylneuraminic acid (Neu5Ac) by cytidine-5′-monophospho-N acetylneuraminic acid hydroxylase (CMAH), which is encoded by the CMAH gene.
Yumiko Uno +3 more
doaj +1 more source
Differential lectin binding patterns in the oviductal ampulla of the horse during oestrus [PDF]
, 2005 We investigated the oligosaccharide sequence of glycoconjugates, mainly sialoglycoconjugates, in the horse oviductal ampulla during oestrus by means of lectin and pre-lectin methods such as the KOH-neuraminidase procedure to remove sialic acid ...
Acone, Franca +7 more
core
Effect of Neu5Ac supplementation on learning and memory in weanling rats and rat pups [PDF]
, 2016 研究背景：新生儿生长发育对营养物质有特殊的要求，任何营养素的匮乏对机体的正常生长和器官结构功能的发育都有深远影响，对脑发育的影响尤为重要。早期营养对大脑的结构和功能有着不可逆转的影响，一旦错过大脑发育的关键期，产生的缺陷后天将无法弥补。新生儿期营养素的缺乏会影响其认知功能。 N-乙酰神经氨酸（N-acetylneuraminicacids，Neu5Ac）是人体中最常见的唾液酸。Neu5Ac在人体中普遍存在，在脑组织及母乳中含量较高；唾液酸作用于神经元细胞膜及突触，在神经系统中产生重要作用 ...
卞冬生
core
N-Acetylneuraminic Acid Inhibits Melanogenesis via Induction of Autophagy
CosmeticsN-acetylneuraminic acid (Neu5Ac) is the predominant form of sialic acid present in the glossy swiftlet (Collocalia esculenta). It is also the only form of sialic acid detected in the human body.
Kei Yoshikawa, Kazuhisa Maeda
doaj +1 more source
DairySialic acids (SIAs) are bioactive compounds present in glycoproteins and glycolipids, playing key roles in human physiology. N-acetylneuraminic acid (Neu5Ac), the only sialic acid synthesized by humans, contributes to neurodevelopment and immune function,
Simona Rinaldi +5 more
doaj +1 more source
PLoS Pathogens, 2015 Neisseria gonorrhoeae deploys a novel immune evasion strategy wherein the lacto-N-neotetraose (LNnT) structure of lipooligosaccharide (LOS) is capped by the bacterial sialyltransferase, using host cytidine-5'-monophosphate (CMP)-activated forms of the ...
Sunita Gulati +18 more
doaj +1 more source
Chemical Synthesis of Sialyl Glycosides for Elucidation of Biological Phenomena [PDF]
, 2014 糖質に分類されるシアル酸は、様々な生体機能を有していることが知られている。従って、シアル酸を含む糖鎖を化学合成することは、生命現象の解明に寄与するものと考えられる。しかし、シアル酸を糖供与体とする糖鎖合成は困難とされており、近年多くの研究者らによって、新たな処方が開発されてきている。我々は、シアル酸が持つ生体機能の興味を持ち、これを有する糖鎖誘導体 (5) の合成を試みた。The sialic acids are now defined as a family of carbohydrates ...
Isao OHTSUKA +11 more
core
Communications BiologySeveral bacterial flagellins are O-glycosylated with nonulosonic acids on surface-exposed Serine/Threonine residues by Maf glycosyltransferases. The Clostridium botulinum Maf glycosyltransferase (CbMaf) displays considerable donor substrate promiscuity ...
Sonali Sunsunwal +3 more
doaj +1 more source
Synthesis of a novel CMP-Neu5Ac analogue : CMP-[a-Neu5Ac (2-8) -Neu5Ac].
Synthesis of a novel CMP-Neu5Ac analogue : CMP-[a-Neu5Ac (2-8) -Neu5Ac].identifier:oai:t2r2.star.titech.ac.jp ...
openaire
Simultaneous ManNAc and Neu5Ac Quantification in Human Sera by LC-MS/MS. [PDF]
Int J Mol SciGuerrero-Flores GN +10 more
europepmc +1 more source