Results 91 to 100 of about 337,560 (313)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Estudo in vitro do papel da matriz extracelular na morfogênese da crista neural cefálica de camundongos [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-graduação em Neurociências.Efeito de Fibronectina, Laminina e Colágeno tipo IV nos processos de migração, morte, proliferação e diferenciação ...
Silva, Bruno Costa da
core  

Mimicking natural neural encoding through retinal electrostimulation

, 2017
Retinal neuroprostheses or `bionic eyes', aim to restore patterned vision to those with vision loss by electrically stimulating the remaining neurons in the degenerate retina.
Dokos, Socrates, John W. Morley, Gregg J. Suaning, David Tsai, Suaning, Gregg J., Barriga-Rivera, Alejandro, Tsai, David, Nigel H. Lovell, Morley, John W. (R12018), Tianruo Guo, Socrates Dokos, Guo, Tianruo, Lovell, Nigel H., Alejandro Barriga-Rivera   +13 more
core   +1 more source

Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology. [PDF]

Am J Alzheimers Dis Other Demen, 2022
Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR.   +4 more
europepmc   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Conveying tactile object characteristics through customized intracortical microstimulation of the human somatosensory cortex

Nature Communications
Microstimulation of the somatosensory cortex can evoke tactile percepts in people with spinal cord injury, providing a means to restore touch. While location and intensity can be reliably conveyed, two issues that prevent creating more complex ...
Ceci Verbaarschot, Vahagn Karapetyan, Charles M. Greenspon, Michael L. Boninger, Sliman J. Bensmaia, Bettina Sorger, Robert A. Gaunt   +6 more
doaj   +1 more source

Graph Structured Neural Networks for Perturbation Biology

Computational modeling of perturbation biology identifies relationships between molecular elements and cellular response, and an accurate understanding of these systems will support the full realization of precision medicine. Traditional deep learning, while often accurate in predicting response, is unlikely to capture the true sequence of involved ...
Nathaniel J. Evans, Gordon B. Mills, Guanming Wu, Xubo Song, Shannon McWeeney   +4 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

ARTIFICIAL NEURAL NETWORKS AND THEIR APPLICATIONS IN BUSINESS [PDF]

In modern software implementations of artificial neural networks the approach inspired by biology has more or less been abandoned for a more practical approach based on statistics and signal processing. In some of these systems, neural networks, or parts
Iordache Ana Maria Mihaela
core  

Single-cell transcriptome analysis reveals mechanisms by which hippocampal deep brain stimulation promotes neurorepair and microglial subpopulation remodeling in ischemic stroke

Journal of Translational Medicine
Background In patients with ischemic stroke, the hippocampus is one of the most severely damaged regions of the brain; however, the optimal parameters for hippocampal deep brain stimulation in these patients remain unknown.
Xuyu Zhao, Yiyang Cao, Xiao Li, Peiru Wu, Jianxin Zhou, Qing Zou, Huanle Hong, Jingying Huang, Rabia Sultan, Jiao Wang   +9 more
doaj   +1 more source