Results 91 to 100 of about 858,608 (347)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Łukasiewicz-Topos Models of Neural Networks, Cell Genome and Interactome Nonlinear Dynamic Models [PDF]

, 2004
A categorical and Łukasiewicz-Topos framework for Algebraic Logic models of nonlinear dynamics in complex functional systems such as Neural Networks, Cell Genome and Interactome Networks is introduced.
Baianu, Professor I.C.
core  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Oriented tensor reconstruction: tracing neural pathways from diffusion tensor MRI [PDF]

, 2002
In this paper we develop a new technique for tracing anatomical fibers from 3D tensor fields. The technique extracts salient tensor features using a local regularization technique that allows the algorithm to cross noisy regions and bridge gaps in the ...
Barr, Alan H., Zhukov, Leonid
core  

Descending pathways from hypothalamus to dorsal motor vagus and ambiguus nuclei in the rat [PDF]

, 1984
The anatomical pathways between the hypothalamus and cell groups of the lower medulla that are involved in the neural control of endocrine pancreas activity were investigated.
Bellinger, Bellinger, Bereiter, Bergman, Berthoud, Berthoud, Bloom, Bloom, Brown, Chung, Cyprian Weaver, De Olmos, F. Kuipers, Frohman, G.J. ter Horst, Grofová, Groot, Herkenham, Hosoya, Ionescu, Jong, Kaneto, Kita, Krieger, Kuypers, Leibowitz, Lobera, Luiten, Mantyh, Marchand, P.G.M. Luiten, Palkovits, Pellegrino, Rogers, Saper, Saper, Saper, Shammah-Lagnado, Shimazu, Sofroniew, Steffens, Steffens, Sugimoto, Yoshida, Yoshimatsu   +44 more
core   +3 more sources

Neural pathways underlying vocal control

Neuroscience & Biobehavioral Reviews, 2002
Vocalization is a complex behaviour pattern, consisting of essentially three components: laryngeal activity, respiratory movements and supralaryngeal (articulatory) activity. The motoneurones controlling this behaviour are located in various nuclei in the pons (trigeminal motor nucleus), medulla (facial nucleus, nucl. ambiguus, hypoglossal nucleus) and
openaire   +4 more sources

The Poole-Frenkel laws and a pathway to multi-valued memory [PDF]

, 2019
We revisit the mechanism of Poole-Frenkel non-ohmic conduction in materials of non-volatile memory. Percolation theory is shown to explain both the Poole and Frenkel dependencies corresponding to the cases of respectively small and large samples compared to the correlation radii of their percolation clusters.
arxiv   +1 more source

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

FEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya, Ksenia V. Sergeeva, Boris S. Shenkman, Timur M. Mirzoev   +3 more
wiley   +1 more source

Art meets science – empowering stroke patients to regain muscular control through creative graphics technology, psycho-physiology and neuroplasticity. [PDF]

, 2012
Treating patients with a cerebrovascular accident or stroke is complicated by severity and site of brain lesion. Muscular control is lost when neural pathways are interrupted or damaged due to embolus, thrombosis or ruptured aneurysm.
Thompson, Simon
core  

Vision at A Glance: Interplay between Fine and Coarse Information Processing Pathways [PDF]

arXiv, 2020
Object recognition is often viewed as a feedforward, bottom-up process in machine learning, but in real neural systems, object recognition is a complicated process which involves the interplay between two signal pathways. One is the parvocellular pathway (P-pathway), which is slow and extracts fine features of objects; the other is the magnocellular ...
arxiv