Results 31 to 40 of about 775,045 (195)

Leptin signaling and leptin resistance

open access: yesMedical Review, 2022
With the prevalence of obesity and associated comorbidities, studies aimed at revealing mechanisms that regulate energy homeostasis have gained increasing interest. In 1994, the cloning of leptin was a milestone in metabolic research. As an adipocytokine,
Liu Jiarui   +3 more
doaj   +1 more source

Postnatal development of retrosplenial projections to the parahippocampal region of the rat

open access: yeseLife, 2016
The rat parahippocampal region (PHR) and retrosplenial cortex (RSC) are cortical areas important for spatial cognition. In PHR, head-direction cells are present before eye-opening, earliest detected in postnatal day (P)11 animals.
Jørgen Sugar, Menno P Witter
doaj   +1 more source

Redundant neural vision systems: competing for collision recognition roles [PDF]

open access: yes, 2013
Ability to detect collisions is vital for future robots that interact with humans in complex visual environments. Lobula giant movement detectors (LGMD) and directional selective neurons (DSNs) are two types of identified neurons found in the visual ...
Rind, F. Claire, Yue, Shigang
core   +1 more source

Hippo-Yap Pathway Orchestrates Neural Crest Ontogenesis [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Neural crest (NC) cells are a migratory stem cell population in vertebrate embryogenesis that can give rise to multiple cell types, including osteoblasts, chondrocytes, smooth muscle cells, neurons, glia, and melanocytes, greatly contributing to the development of different tissues and organs.
Zhao, Xiaolei   +4 more
openaire   +4 more sources

Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response. [PDF]

open access: yes, 2013
BackgroundTraumatic brain injury (TBI) results in irreversible damage at the site of impact and initiates cellular and molecular processes that lead to secondary neural injury in the surrounding tissue.
Ford, Byron D   +5 more
core   +2 more sources

Regulation of Neural Circuitry under General Anesthesia: New Methods and Findings

open access: yesBiomolecules, 2022
General anesthesia has been widely utilized since the 1840s, but its underlying neural circuits remain to be completely understood. Since both general anesthesia and sleep are reversible losses of consciousness, studies on the neural-circuit mechanisms ...
Kai Zhang, Jiacheng Pan, Yonghao Yu
doaj   +1 more source

Brain-based correlates of depression and traumatic brain injury: a systematic review of structural and functional magnetic resonance imaging studies

open access: yesFrontiers in Neuroimaging
IntroductionDepression is prevalent after traumatic brain injury (TBI). However, there is a lack of understanding of the brain-based correlates of depression post-TBI.
Vanessa A. Baltazar   +12 more
doaj   +1 more source

Parallel Development of Chromatin Patterns, Neuron Morphology, and Connections: Potential for Disruption in Autism

open access: yesFrontiers in Neuroanatomy, 2018
The phenotype of neurons and their connections depend on complex genetic and epigenetic processes that regulate the expression of genes in the nucleus during development and throughout life.
Miguel Á García-Cabezas   +4 more
doaj   +1 more source

Caldesmon regulates actin dynamics to influence cranial neural crest migration in Xenopus [PDF]

open access: yes, 2011
Caldesmon (CaD) is an important actin modulator that associates with actin filaments to regulate cell morphology and motility. Although extensively studied in cultured cells, there is little functional information regarding the role of CaD in migrating ...
Bronner-Fraser, Marianne   +2 more
core   +2 more sources

Vagal nerve stimulation therapy: what is being stimulated? [PDF]

open access: yes, 2014
Vagal nerve stimulation in cardiac therapy involves delivering electrical current to the vagal sympathetic complex in patients experiencing heart failure. The therapy has shown promise but the mechanisms by which any benefit accrues is not understood. In
Ardell, Jeffrey L   +3 more
core   +11 more sources

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