Results 61 to 70 of about 4,814,544 (359)

Direct neural pathways convey distinct visual information to Drosophila mushroom bodies

open access: yeseLife, 2016
Previously, we demonstrated that visual and olfactory associative memories of Drosophila share mushroom body (MB) circuits (Vogt et al., 2014). Unlike for odor representation, the MB circuit for visual information has not been characterized.
K. Vogt   +8 more
semanticscholar   +1 more source

Building and manipulating neural pathways with microfluidics [PDF]

open access: yesLab on a Chip, 2010
Communication between different brain regions, and between local circuits in the same brain region, is an important area of study for basic and translational neuroscience research. Selective and chronic manipulation of one of the components in a given neural pathway is frequently required for development and plasticity studies.
Yevgeny Berdichevsky   +2 more
openaire   +2 more sources

Vagal nerve stimulation therapy: what is being stimulated? [PDF]

open access: yes, 2014
Vagal nerve stimulation in cardiac therapy involves delivering electrical current to the vagal sympathetic complex in patients experiencing heart failure. The therapy has shown promise but the mechanisms by which any benefit accrues is not understood. In
Ardell, Jeffrey L   +3 more
core   +3 more sources

Visual pathways from the perspective of cost functions and multi-task deep neural networks [PDF]

open access: yes, 2017
Vision research has been shaped by the seminal insight that we can understand the higher-tier visual cortex from the perspective of multiple functional pathways with different goals. In this paper, we try to give a computational account of the functional
Bohte, Sander M.   +4 more
core   +2 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

A Connectomic Analysis of the Human Basal Ganglia Network

open access: yesFrontiers in Neuroanatomy, 2017
The current model of basal ganglia circuits has been introduced almost two decades ago and has settled the basis for our understanding of basal ganglia physiology and movement disorders.
Alberto Cacciola   +11 more
doaj   +1 more source

Vestibular Pharmacology and Neural Pathway

open access: yesPractica Oto-Rhino-Laryngologica, 1983
This paper deals with recent advances in anatomical, biochemical, pharmacological and physiological studies on the vestibular system. Fiber connections and characteristics of the vestibular neurons and primary vestibular neurons were discussed in relation to other structures such as the cerebellum, oculomotor nuclei, reticular formation, and spinal ...
Haruo Takahashi   +4 more
openaire   +3 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

The role of axon guidance molecules in the pathogenesis of epilepsy

open access: yesNeural Regeneration Research
Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms
Zheng Liu, Chunhua Pan, Hao Huang
doaj   +1 more source

Pathogenicity of Endocrine Dysregulation in Autism: The Role of the Melanin-Concentrating Hormone System

open access: yesSciMedicine Journal, 2019
The voluminous daily output of autism research has become increasingly disconnected, existing largely within highly specific subspecialty areas, and lacking cross-disciplinary linkages of context, theory, and findings to inform a unified body of ...
Adam Swierczynski
doaj   +1 more source

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