Results 1 to 10 of about 93,309 (296)
Frontiers in Aging Neuroscience, 2021 Aging changes the mechanical properties of brain tissue, such as stiffness. It has been proposed that the maintenance and differentiation of neural stem cells (NSCs) are regulated in accordance with extracellular stiffness.
Youngjae Ryu +4 more
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A novel retinal ganglion cell quantification tool based on deep learning
Scientific Reports, 2021 Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin +7 more
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MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System
Cells, 2021 Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries +11 more
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Biomedicines, 2022 We studied the phenotypes in an oligodendrocyte genesis site at the acute stage of spinal cord injury, when we observed regenerated ascending neurites. Pan-oligodendrocyte marker OLIG2+ cells were more in fibroblast growth factor (FGF)-1-treated rats (F ...
Meng-Jen Lee +9 more
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Journal of Biomedical Science, 2017 Background Olfactory ensheathing cells (OEC), specialized glia that ensheathe bundles of olfactory nerves, have been reported as a favorable substrate for axonal regeneration.
May-Jywan Tsai +14 more
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Journal of Neuroinflammation, 2022 Background Alcohol use disorders result from repeated binge and chronic alcohol consumption followed by negative effects, such as anxiety, upon cessation. This process is associated with the activation of NLRP3 inflammasome-mediated responses.
Ziyi Li +9 more
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Frontiers in Immunology, 2023 Sialic acids are terminal sugars of the cellular glycocalyx and are highly abundant in the nervous tissue. Sialylation is sensed by the innate immune system and acts as an inhibitory immune checkpoint.
Tawfik Abou Assale +5 more
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Clinical and Applied Thrombosis/Hemostasis, 2021 Background: To investigate the factors associated with elevated fibrinogen (Fbg) levels in COVID-19 patients with and without diabetes (DM) and impaired fasting glucose (IFG).
Zhenzhou Wang MD +5 more
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MicroRNA-142a-3p regulates neurogenic skeletal muscle atrophy by targeting Mef2a
Molecular Therapy: Nucleic Acids, 2023 Peripheral nerve injury can lead to progressive muscle atrophy and poor motor function recovery, which is a difficult point of treatment, and the mechanism needs to be further explored.
Xinyi Gu +7 more
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Depressive patient‐derived GABA interneurons reveal abnormal neural activity associated with HTR2C
EMBO Molecular Medicine, 2022 Major depressive disorder with suicide behavior (sMDD) is a severe mood disorder, bringing tremendous burden to family and society. Although reduced gamma amino butyric acid (GABA) level has been observed in postmortem tissues of sMDD patients, the ...
Kaiqin Lu +11 more
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