Glycogen synthase kinase 3 signaling in neural regeneration in vivo. [PDF]
J Mol Cell Biol, 2023 Glycogen synthase kinase 3 (GSK3) signaling plays important and broad roles in regulating neural development in vitro and in vivo. Here, we reviewed recent findings of GSK3-regulated axon regeneration in vivo in both the peripheral and central nervous ...
Zhang J, Yang SG, Zhou FQ.
europepmc +2 more sources
Therapeutic advances in neural regeneration for Huntington's disease. [PDF]
Neural Regen Res, 2023 Huntington's disease is a neurodegenerative disease caused by the expansion mutation of a cytosine-adenine-guanine triplet in the exon 1 of the HTT gene which is responsible for the production of the huntingtin (Htt) protein. In physiological conditions,
D'Egidio F +6 more
europepmc +2 more sources
Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration. [PDF]
Adv Sci (Weinh)Epigenetic regulation of neuronal transcriptomic landscape is emerging to be a key coordinator of mammalian neural regeneration. The roles of two histone 3 lysine 27 (H3K27) demethylases, Kdm6a/b, in controlling neuroprotection and axon regeneration are ...
Yang SG +13 more
europepmc +2 more sources
Biomaterials and tissue engineering in traumatic brain injury: novel perspectives on promoting neural regeneration. [PDF]
Neural Regen Res, 2023 Traumatic brain injury is a serious medical condition that can be attributed to falls, motor vehicle accidents, sports injuries and acts of violence, causing a series of neural injuries and neuropsychiatric symptoms. However, limited accessibility to the
Zhu S +9 more
europepmc +2 more sources
Microglia dynamic response and phenotype heterogeneity in neural regeneration following hypoxic-ischemic brain injury. [PDF]
Front Immunol, 2023 Hypoxic-ischemic brain injury poses a significant threat to the neural niche within the central nervous system. In response to this pathological process, microglia, as innate immune cells in the central nervous system, undergo rapid morphological ...
Quan H, Zhang R.
europepmc +2 more sources
Revolutionizing neural regeneration with smart responsive materials: Current insights and future prospects. [PDF]
Bioact MaterSmart-responsive materials, which possess the capacity to receive signals from the environment and engage in dynamic communication with it, have significantly expanded the frontiers of tissue engineering and regenerative medicine.
Gao H +9 more
europepmc +2 more sources
All-in-one smart dressing for simultaneous angiogenesis and neural regeneration. [PDF]
J Nanobiotechnology, 2023 Wound repair, along with skin appendage regeneration, is challenged by insufficient angiogenesis and neural regeneration. Therefore, promoting both proangiogenic and neuro-regenerative therapeutic effects is essential for effective wound repair. However,
Yuan T +7 more
europepmc +2 more sources
Cutting-edge technologies in neural regeneration [PDF]
Cell RegenerationNeural regeneration stands at the forefront of neuroscience, aiming to repair and restore function to damaged neural tissues, particularly within the central nervous system (CNS), where regenerative capacity is inherently limited.
Chang-Ping Li +6 more
doaj +2 more sources
Hydrogels for Neural Regeneration: Exploring New Horizons. [PDF]
Materials (Basel)Nerve injury can significantly impair motor, sensory, and autonomic functions. Understanding nerve degeneration, particularly Wallerian degeneration, and the mechanisms of nerve regeneration is crucial for developing effective treatments. This manuscript
Omidian H, Chowdhury SD, Cubeddu LX.
europepmc +2 more sources
The Promising Role of a Zebrafish Model Employed in Neural Regeneration Following a Spinal Cord Injury. [PDF]
Int J Mol Sci, 2023 Spinal cord injury (SCI) is a devastating event that results in a wide range of physical impairments and disabilities. Despite the advances in our understanding of the biological response to injured tissue, no effective treatments are available for SCIs ...
Zeng CW, Tsai HJ.
europepmc +2 more sources