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Cutting-edge technologies in neural regeneration [PDF]

open access: yesCell Regeneration
Neural regeneration stands at the forefront of neuroscience, aiming to repair and restore function to damaged neural tissues, particularly within the central nervous system (CNS), where regenerative capacity is inherently limited.
Chang-Ping Li   +6 more
doaj   +2 more sources

Harnessing migraines for neural regeneration

open access: goldNeural Regeneration Research, 2018
The success of naturalistic or therapeutic neuroregeneration likely depends on an internal milieu that facilitates the survival, proliferation, migration, and differentiation of stem cells and their assimilation into neural networks. Migraine attacks are an integrated sequence of physiological processes that may protect the brain from oxidative stress ...
Jonathan M. Borkum
openalex   +4 more sources

Nanobiomaterials for neural regeneration

open access: goldNeural Regeneration Research, 2016
Diseases and disorders associated with nervous system such as injuries by trauma and neurodegeneration are shown to be one of the most serious problems in medicine, requiring innovative strategies to trigger and enhance the nerve regeneration. Tissue engineering aims to provide a highly biomimetic environment by using a combination of cells, materials ...
Seeram Ramakrishna   +3 more
openalex   +4 more sources

Magnetic Composite Biomaterials for Neural Regeneration [PDF]

open access: goldFrontiers in Bioengineering and Biotechnology, 2019
Nervous system damage caused by physical trauma or degenerative diseases can result in loss of sensory and motor function for patients. Biomaterial interventions have shown promise in animal studies, providing contact guidance for extending neurites or sustained release of various drugs and growth factors; however, these approaches often target only ...
Jessica L. Funnell   +2 more
openalex   +4 more sources

A Shift in Tissue Stiffness During Hippocampal Maturation Correlates to the Pattern of Neurogenesis and Composition of the Extracellular Matrix

open access: yesFrontiers in Aging Neuroscience, 2021
Aging changes the mechanical properties of brain tissue, such as stiffness. It has been proposed that the maintenance and differentiation of neural stem cells (NSCs) are regulated in accordance with extracellular stiffness.
Youngjae Ryu   +4 more
doaj   +1 more source

A novel retinal ganglion cell quantification tool based on deep learning

open access: yesScientific Reports, 2021
Glaucoma is a disease associated with the loss of retinal ganglion cells (RGCs), and remains one of the primary causes of blindness worldwide. Major research efforts are presently directed towards the understanding of disease pathogenesis and the ...
Luca Masin   +7 more
doaj   +1 more source

MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System

open access: yesCells, 2021
Neuroinflammation has been put forward as a mechanism triggering axonal regrowth in the mammalian central nervous system (CNS), yet little is known about the underlying cellular and molecular players connecting these two processes.
Lien Andries   +11 more
doaj   +1 more source

Exogenous FGF-1 Differently Regulates Oligodendrocyte Replenishment in an SCI Repair Model and Cultured Cells

open access: yesBiomedicines, 2022
We studied the phenotypes in an oligodendrocyte genesis site at the acute stage of spinal cord injury, when we observed regenerated ascending neurites. Pan-oligodendrocyte marker OLIG2+ cells were more in fibroblast growth factor (FGF)-1-treated rats (F ...
Meng-Jen Lee   +9 more
doaj   +1 more source

Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair

open access: yesJournal of Biomedical Science, 2017
Background Olfactory ensheathing cells (OEC), specialized glia that ensheathe bundles of olfactory nerves, have been reported as a favorable substrate for axonal regeneration.
May-Jywan Tsai   +14 more
doaj   +1 more source

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