Results 1 to 10 of about 1,237,621 (358)
The Journal of Pathology, 2002 AbstractNeural stem cells (NSCs) have the ability to self‐renew, and are capable of differentiating into neurones, astrocytes and oligodendrocytes. Such cells have been isolated from the developing brain and more recently from the adult central nervous system. This review aims to provide an overview of the current research in this evolving area.
Tanja Zigova +2 more
+7 more sources
Therapeutic Plasticity of Neural Stem Cells [PDF]
Frontiers in Neurology, 2020 Neural stem cells (NSCs) have garnered significant scientific and commercial interest in the last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes inside and outside of the nervous system, with a capacity of ...
L. Ottoboni +2 more
semanticscholar +6 more sources
Bone Marrow Transplantation, 2003 The adult vertebrate central nervous system (CNS) consists of four major differentiated cell types: neurons, astrocytes, oligodendrocytes and ependymal cells. Historically, there has been a disagreement on how these differentiated cell types are generated in the CNS. Progress remains hindered by the complexity of cell structure in this system, the lack
Rossella Galli +3 more
+9 more sources
Roles of neural stem cells in the repair of peripheral nerve injury
Neural Regeneration Research, 2017 Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair.
Chong Wang +4 more
doaj +2 more sources
Flexibility of neural stem cells [PDF]
Frontiers in Physiology, 2011 Embryonic cortical neural stem cells are self-renewing progenitors that can differentiate into neurons and glia. We generated neurospheres from the developing cerebral cortex using a mouse genetic model that allows for lineage selection and found that ...
Eumorphia eRemboutsika +7 more
doaj +5 more sources
Frontiers in Neuroscience, 2022 Postnatal and adult neurogenesis takes place in the dentate gyrus of the hippocampus in the vast majority of mammals due to the persistence of a population of neural stem cells (NSCs) that also generate astrocytes and more NSCs.
Ane Rodríguez-Bodero +4 more
doaj +1 more source
Cells, 2023 The Neurovascular Unit (NVU), composed of glia (astrocytes, oligodendrocytes, microglia), neurons, pericytes and endothelial cells, is a dynamic interface ensuring the physiological functioning of the central nervous system (CNS), which gets affected and
Evangelia Xingi +8 more
doaj +1 more source
Neural Regeneration Research, 2022 [INLINE:1] Brain lesions can cause neural stem cells to activate, proliferate, differentiate, and migrate to the injured area. However, after traumatic brain injury, brain tissue defects and microenvironment changes greatly affect the survival and growth
Xuan-Yu Fang +8 more
doaj +1 more source
Neural Regeneration Research, 2021 Transplantation of neural stem cells (NSCs) can protect neurons in animal stroke models; however, their low rates of survival and neuronal differentiation limit their clinical application.
Sheng-Jun Wen +6 more
doaj +1 more source
Neural Stem Cells and Stroke [PDF]
Cell Transplantation, 2013 Acute ischemic stroke causes a disturbance of neuronal circuitry and disruption of the blood–brain barrier that can lead to functional disabilities. At present, thrombolytic therapy inducing recanalization of the occluded vessels in the cerebral infarcted area is a commonly used therapeutic strategy.
Chen Huan Lin +3 more
openaire +3 more sources