Results 21 to 30 of about 204,825 (175)

Characterization of TLX expression in neural stem cells and progenitor cells in adult brains. [PDF]

open access: yesPLoS ONE, 2012
TLX has been shown to play an important role in regulating the self-renewal and proliferation of neural stem cells in adult brains. However, the cellular distribution of endogenous TLX protein in adult brains remains to be elucidated.
Shengxiu Li   +4 more
doaj   +1 more source

Perspective: Of Mice and Men – How Widespread Is Adult Neurogenesis?

open access: yesFrontiers in Neuroscience, 2019
These are exciting times for research on adult hippocampal neurogenesis (AHN). Debate and controversy regarding the existence of generation of new neurons in the adult, and even diseased human brain flourishes as articles against and in favor accumulate.
David Petrik   +5 more
doaj   +1 more source

Stem Cells, Neural Progenitors, and Engineered Stem Cells [PDF]

open access: yes, 2014
Human pluripotent stem cells (hPSCs ) have the unique potential to form every cell type in the body. This potential provides opportunities for generating human progenitors and other differentiated cell types for understanding human development and for use in cell type-specific therapies. Equally important is the ability to engineer stem cells and their
Raj R, Rao, Shilpa, Iyer
openaire   +2 more sources

Transplantation of erythropoietin gene-modified neural stem cells improves the repair of injured spinal cord

open access: yesNeural Regeneration Research, 2015
The protective effects of erythropoietin on spinal cord injury have not been well described. Here, the eukaryotic expression plasmid pcDNA3.1 human erythropoietin was transfected into rat neural stem cells cultured in vitro.
Min-fei Wu   +5 more
doaj   +1 more source

Oscillating field stimulation promotes neurogenesis of neural stem cells through miR-124/Tal1 axis to repair spinal cord injury in rats

open access: yesNeural Regeneration Research, 2023
Spinal cord injury often leads to severe motor and sensory deficits, and prognosis using the currently available therapies remains poor. Therefore, we aimed to explore a novel therapeutic approach for improving the prognosis of spinal cord injury.
Chao Fang   +3 more
doaj   +1 more source

Neural stem cell secretome and its role in the treatment of neurodegenerative disorders [PDF]

open access: yesJournal of Integrative Neuroscience, 2020
Neurological diseases in the central nervous system are mostly characterized by the failure of endogenous repair to restore tissue damage and salvage lost function.
Qian Zhang, Jia Li , Wenqiang An, Yiou Fan, Qilong Cao
doaj   +1 more source

New insights into the biological roles of immune cells in neural stem cells in post-traumatic injury of the central nervous system

open access: yesNeural Regeneration Research, 2023
Traumatic injuries in the central nervous system, such as traumatic brain injury and spinal cord injury, are associated with tissue inflammation and the infiltration of immune cells, which simultaneously affect the self-renewal and differentiation of ...
Ning He   +5 more
doaj   +1 more source

Updated Toolbox for Assessing Neuronal Network Reconstruction after Cell Therapy

open access: yesBioengineering
Cell therapy has proven to be a promising treatment for a range of neurological disorders, including Parkinson Disease, drug-resistant epilepsy, and stroke, by restoring function after brain damage.
Ana Gonzalez-Ramos   +3 more
doaj   +1 more source

Roles of neural stem cells in the repair of peripheral nerve injury

open access: yesNeural Regeneration Research, 2017
Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair.
Chong Wang   +4 more
doaj   +1 more source

Cell cycle exit and neuronal differentiation 1-engineered embryonic neural stem cells enhance neuronal differentiation and neurobehavioral recovery after experimental traumatic brain injury

open access: yesNeural Regeneration Research, 2022
Our previous study showed that cell cycle exit and neuronal differentiation 1 (CEND1) may participate in neural stem cell cycle exit and oriented differentiation. However, whether CEND1-transfected neural stem cells can improve the prognosis of traumatic
Ren Wang   +7 more
doaj   +1 more source

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