Results 41 to 50 of about 141,449 (304)

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Effect of retinoic acid on neural tube development in chick embryo [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 1996
retinoic acid is one of the derivatives of vitamin A.it is used for treatment of dermatitis,but it has different teratogenic effects on developing organs depending on the different stages of embryonic life.neural  tube is made of two different parts ...
M Shariati   +3 more
doaj  

Retinoic Acid Signaling during Early Spinal Cord Development

open access: yesJournal of Developmental Biology, 2014
Retinoic acid signaling is required at several steps during the development of the spinal cord, from the specification of generic properties to the final acquisition of neuronal subtype identities, including its role in trunk neural crest development ...
Ruth Diez del Corral, Aixa V. Morales
doaj   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Neural Tube Defects in Iraq

open access: yesمجله كليه طب الكندي, 2013
1. Embryonic Origin of Neural Tube Defects. Insaf Jasim Mahmoud 2. Etiology of Neural Tube Defectss. Ali Abdul Razzak Obed 3. Epidemiology of Neural Tube Defects in Iraq. Mahmood Dhahir Al-Mendalawi 4. Surgical Management of Neural Tube Defects.
Mahmood Dhahir Al-Mendalaw   +3 more
doaj  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Diacylglycerol kinase γ facilitates the proliferation and migration of neural stem cells in the developing neural tube

open access: yesActa Biochimica et Biophysica Sinica
In this study, we aim to investigate diacylglycerol kinase (DGK) γ expression in developing neural tubes (NTs) and its effects on neural stem cell (NSC) proliferation and migration.
Cui Huilin   +8 more
doaj   +1 more source

Glycolytic activity is required for the onset of neural plate folding during neural tube closure in mouse embryos

open access: yesFrontiers in Cell and Developmental Biology, 2023
Physiological hypoxia is critical for placental mammalian development. However, the underlying mechanisms by which hypoxia regulates embryonic development remain unclear.
Daisuke Sakai   +6 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Inositol, neural tube closure and the prevention of neural tube defects

open access: yesBirth Defects Research, 2017
Susceptibility to neural tube defects (NTDs), such as anencephaly and spina bifida is influenced by genetic and environmental factors including maternal nutrition. Maternal periconceptional supplementation with folic acid significantly reduces the risk of an NTD‐affected pregnancy, but does not prevent all NTDs, and “folic acid non‐responsive” NTDs ...
Greene, ND, Leung, KY, Copp, AJ
openaire   +3 more sources

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