Results 81 to 90 of about 1,866,573 (308)

Youngstown Sheet and Tube Company's Hubbard Works

, 1910
This is an early photograph of Youngstown Sheet and Tube Company's Hubbard Works, in Hubbard, Ohio, ca. 1910-1919. Part of Youngstown Sheet and Tube Company's Youngstown District, the Hubbard Works was one of the first steel mills acquired by ...
Youngstown Sheet and Tube Company
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Architecture‐Driven Functional Coupling in Vertically Aligned Nanocomposites

Advanced Functional Materials, EarlyView.
Vertically aligned nanocomposites define a growth‐engineered architecture in which vertical interfaces, strain fields, defect pathways, and phase connectivity are created simultaneously. This review shows how these architectural features couple ferroic, optical, ionic, electrochemical, and device responses, establishing design rules and open challenges
Md Shatil Islam‐Shanto, Javier Zamudio‐García, Abraham Sánchez‐Caballero, David Marrero‐López, Vincenzo Esposito   +4 more
wiley   +1 more source

Wnt-dependent mechanism of the apical constriction of roof plate cells in developing mouse spinal cord

Frontiers in Cell and Developmental Biology
Apical constriction of epithelial cells usually occurs in a local portion of epithelial sheet, which results in bending of epithelial tissues. However, it is uncertain whether diffusible signal molecules, like Wnt, regulate such locally restricted events.
Takuma Shinozuka, Takuma Shinozuka, Takuma Shinozuka, Tadashi Okubo, Noriaki Sasai, Shinji Takada, Shinji Takada, Shinji Takada   +7 more
doaj   +1 more source

Folate deficiency induced H2A ubiquitination to lead to downregulated expression of genes involved in neural tube defects

Epigenetics & Chromatin, 2019
Background Neural tube defects (NTDs) are common congenital malformations resulting in failure of the neural tube closure during early embryonic development.
Pei Pei, Xiyue cheng, Juan Yu, Jinying Shen, Xue Li, Jianxin Wu, Shan Wang, Ting Zhang   +7 more
doaj   +1 more source

Reducing the risk of a neural tube birth defect [PDF]

This information is for families who have had a pregnancy affected by a neural tube defect.CS124497NTD_Card_English508 ...

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A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitors

eLife
During neural tube patterning, a gradient of Sonic hedgehog (Shh) signaling specifies ventral progenitor fates. The cellular response to Shh is processed through a genetic regulatory network (GRN) to specify distinct fate decisions.
Fengzhu Xiong, Andrea R Tentner, Sandy Nandagopal, Tom W Hiscock, Peng Huang, Sean G Tsung-Megason   +5 more
doaj   +1 more source

Countries and organizations united for neural tube defects prevention : at-a-glance [PDF]

Neural tube defects are serious birth defects that occur along the neural tube and are a significant cause of death and lifelong disability worldwide. The two most common neural tube defects are spina bifida and anencephaly (1).Spina bifida happens when ...

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Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Youngstown Sheet and Tube Company's Campbell Works

, 1920
A view of Youngstown Sheet and Tube Company's Campbell Works, in East Youngstown (Campbell), Ohio, ca. 1920-1929. Named after company founder James Campbell, the Campbell Works was Youngstown Sheet and Tube Company's first steel mill and was also its ...
Youngstown Sheet and Tube Company
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