Results 21 to 30 of about 2,001,908 (203)

RGMa and RGMb expression pattern during chicken development suggest unexpected roles for these repulsive guidance molecules in notochord formation, somitogenesis, and myogenesis [PDF]

open access: yes, 2012
Background: Repulsive guidance molecules (RGM) are high-affinity ligands for the Netrin receptor Neogenin, and they are crucial for nervous system development including neural tube closure; neuronal and neural crest cell differentiation and axon guidance.
Coutinho, L.   +9 more
core   +1 more source

Impact of prenatal exposure to metallic elements on neural tube defects: Insights from human investigations

open access: yesEcotoxicology and Environmental Safety, 2023
Metallic elements play a pivotal role in maternal and fetal health. Metals can cross the placental barrier and be absorbed by fetuses, where they may affect closure of the neural tube during embryonic development. Neural tube defects (NTDs), which result
Wanqi Huang   +3 more
doaj   +1 more source

Neural tube closure: cellular, molecular and biomechanical mechanisms. [PDF]

open access: yes, 2017
Neural tube closure has been studied for many decades, across a range of vertebrates, as a paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the severe congenital malformations - 'neural tube defects' - that result ...
Rolo, A   +9 more
core   +1 more source

Video5_Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development.AVI

open access: yes, 2023
Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects ...
Paris A. Skourides (14347593)   +1 more
core   +1 more source

Aberrant Gcm1 expression mediates Wnt/β-catenin pathway activation in folate deficiency involved in neural tube defects

open access: yesCell Death and Disease, 2021
Wnt signaling plays a major role in early neural development. An aberrant activation in Wnt/β-catenin pathway causes defective anteroposterior patterning, which results in neural tube closure defects (NTDs).
Jianting Li   +13 more
doaj   +1 more source

Video1_Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development.AVI

open access: yes, 2023
Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects ...
Paris A. Skourides (14347593)   +1 more
core   +1 more source

Video4_Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development.AVI

open access: yes, 2023
Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects ...
Paris A. Skourides (14347593)   +1 more
core   +1 more source

Single-cell transcriptomics reveals the cellular identity of a novel progenitor population crucial for murine neural tube closure

open access: yesHeliyon
Neural tube closure in vertebrates is achieved through a highly dynamic and coordinated series of morphogenic events involving neuroepithelium, surface ectoderm, and neural plate border.
Zihao Deng   +7 more
doaj   +1 more source

Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy

open access: yesNature Communications, 2019
Neural tube defects can arise from high glucose levels caused by maternal diabetes, and MARCKS is required for neural tube closure. Here, Yang et al. show that acetylation and phosphorylation of MARCKS in hyperglycemic conditions causes mitochondrial and
Penghua Yang   +8 more
doaj   +1 more source

Video2_Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development.AVI

open access: yes, 2023
Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects ...
Paris A. Skourides (14347593)   +1 more
core   +1 more source

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