Results 61 to 70 of about 12,096 (222)

Noncanonical function of folate through folate receptor 1 during neural tube formation

Nature Communications
Folate supplementation reduces the occurrence of neural tube defects (NTDs), birth defects consisting in the failure of the neural tube to form and close. The mechanisms underlying NTDs and their prevention by folate remain unclear.
Olga A. Balashova, Alexios A. Panoutsopoulos, Olesya Visina, Jacob Selhub, Paul S. Knoepfler, Laura N. Borodinsky   +5 more
doaj   +1 more source

Burden of Neural Tube Defects and Their Associated Factors in Africa: A Systematic Review and Meta-Analysis

International Journal of Pediatrics, 2023
Background. Neural tube defects are a type of congenital anomaly caused by an abnormality in the development of the brain and spinal cord during embryogenesis. They cause high rates of mortality, morbidity, and lifelong disability.
Reta Wakoya, Mekbeb Afework
doaj   +1 more source

Serum copper concentration in newborns with neural tube defects in northern Iran; A case control study [PDF]

, 2009
Objective: This study was conducted to determine the eventual association between copper deficiency in newborns with neural tube defects (NTD) in Northern Iran. A high prevalence of neural tube defects has been reported from this region.
Golalipour, M.-J., Keshtkar, A.-A., Mansourian, A.-R.   +2 more
core  

Potential Impact of Large‐Scale Food Fortification in Ethiopia: Coverage and Knowledge of Fortifiable Foods

Maternal &Child Nutrition, EarlyView.
Coverage of fortifiable oil, salt, and wheat flour by wealth quintiles. ABSTRACT Large‐scale food fortification (LSFF) is an effective public health measure because it may reach a large number of populations at risk using current food delivery systems.
Aregash Samuel, Ramadhani Noor, Nahom Tefera, Alemayehu Hussien, Genet Gebremedhin, Mduduzi Mbuya, Endale Amare, Meseret Woldeyohannes, Getinet Fikresilassie, Meron Girma, Alemnesh Petros, Anbissa Muleta, Bedasa Tessema, Feyissa Chala, Kaleab Baye, Arnaud Laillou, Tesfaye Chuko, Getachew Tollera, Mesay Hailu, Stanley Chitekwe, Masresha Tessema   +20 more
wiley   +1 more source

Administration of prosaposin-derived neurotrophic factor to neural tube defects facilitates regeneration and restores neurological functions

iScience, 2023
Summary: Neural tube defects (NTDs) cause fetal and pediatric deaths or lifelong neurological disabilities. No effective treatment is currently available for NTDs.
Sakirul Khan, Akihide Takeuchi, Hiroaki Nabeka, Farzana Khan, Tetsuya Shimokawa, Sota Takanezawa, Takashi Saitou, Takeshi Imamura, Tetsuya Tachibana, Akira Nishizono, Fumihiko Hamada, Seiji Matsuda   +11 more
doaj   +1 more source

Maternal serum zinc deficiency in cases of neural tube defect in Gorgan, north Islamic Republic of Iran [PDF]

, 2009
Previous studies have shown a high rate of neural tube defects (NTD) in Gorgan, northern Islamic Republic of Iran. This case-control study during 2003-04 compared serum zinc levels and other variables in 23 mothers of neonates affected with NTD and 36 ...
Golalipour, M.J., Mansourian, A.R., Mobasheri, E., Vakili, M.A.   +3 more
core   +1 more source

Serum Folate Concentration Corresponding to the Red Blood Cell Folate Threshold for Increased Risk of Neural Tube Defects Among Ethiopian Women of Reproductive Age

Maternal &Child Nutrition, EarlyView.
ABSTRACT Neural tube defects (NTDs) are severe birth defects linked to insufficient maternal folate status during early pregnancy. Red blood cell (RBC) folate concentration is the recommended biomarker for predicting NTD risk, with a threshold of 748 nmol/L using the US Centers for Disease Control and Prevention (CDC) microbiological assay. However, in
Biniyam Tesfaye, Meseret Woldeyohannes, Masresha Tessema, Charles Dale Arnold, Christine M. McDonald, Kenneth H. Brown   +5 more
wiley   +1 more source

Folate deficiency induced H2A ubiquitination to lead to downregulated expression of genes involved in neural tube defects

Epigenetics & Chromatin, 2019
Background Neural tube defects (NTDs) are common congenital malformations resulting in failure of the neural tube closure during early embryonic development.
Pei Pei, Xiyue cheng, Juan Yu, Jinying Shen, Xue Li, Jianxin Wu, Shan Wang, Ting Zhang   +7 more
doaj   +1 more source

Ethionine Suppresses Mitochondria Autophagy and Induces Apoptosis via Activation of Reactive Oxygen Species in Neural Tube Defects

Frontiers in Neurology, 2020
Abnormal development of central nervous system (CNS) caused by neural tube defects (NTDs) is not only remained the major contributor in the prevalence of stillbirths and neonatal deaths, but also represents a significant cause of lifelong physical ...
Li Zhang, Yanting Dong, Wenzhuo Wang, Taoran Zhao, Tingjuan Huang, Ajab Khan, Lei Wang, Zhizhen Liu, Jun Xie, Bo Niu, Bo Niu   +10 more
doaj   +1 more source

Epidemiologic aspects of neural tube defects in South East Iran [PDF]

, 2006
Objectives: To investigate the rate of neural tube defects (NTDs) and their relation to gender, maternal age, consanguineous marriage, season, and drug consumption in Birjand, Iran.
Afshar, M., Farhud, D., Golalipour, M.J.
core