Results 71 to 80 of about 12,096 (222)
Summary/Abstract Background: Neural tube defects (NTDs) are one of the commonest malformations with worldwide prevalence of 1-3 per1000 live births. They are resulted by failure of neural tube to close during neurulation in 21-28 embryonic days and it’s a multi-factorial in etiology.
Poster Mutambo, Paul Siapiila
openaire +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
One‐carbon metabolism (OCM) nutrients play a critical role in fetal development and are implicated in the etiology of spontaneous pregnancy loss (SPL). In our large cohort study, we report for the first time that paternal red blood cell folate levels ≥ 400 ng/mL—consistent with the World Health Organization's recommendation for neural tube defect ...
Xiaotian Chen +18 more
wiley +1 more source
Exposing imidacloprid interferes with neurogenesis through impacting on chick neural tube cell survival [PDF]
As a neonicotinoid pesticide, imidacloprid is widely used to control insects in agriculture and fleas on domestic animals. However, it is not known whether imidacloprid exposure negatively affects neurogenesis during embryonic development. In this study,
Chao-Jie Wang +17 more
core +2 more sources
Background: Neural Tube Defects (NTDs) are the world's second most common birth defects after cardiovascular defects. In developing countries like Zambia, these defects are unrecognized and under reported. Despite the administration of folic acid, there have been incidences of NTDs though no local literature points out the frequency of these defects ...
Poster, Mutambo, Siapiila, Paul
openaire +2 more sources
A human pilot study with a novel dual isotope design was performed to assess the bioavailability of brewer's yeast folate as a model food. The study‘s outcome was that the folates from intrinsically 15N‐labeled yeast revealed a mean bioavailability of 74 %.
Nadine Weber +7 more
wiley +1 more source
BackgroundNeural tube defects (NTDs) are complex multifactorial disorders in the neurulation of the brain and spinal cord that develop in humans between 21 and 28 days of conception.
Beminet Moges Gebremariam +3 more
doaj +1 more source
Abnormal methylation caused by folic acid deficiency in neural tube defects
Neural tube closure disorders, including anencephaly, spina bifida, and encephalocele, cause neural tube defects (NTDs). This congenital disability remained not only a major contributor to the prevalence of stillbirths and neonatal deaths but also a ...
Cao Rui, Xie Jun, Zhang Li
doaj +1 more source
Knowledge and practice of urban Iranian pregnant women towards folic acid intake for neural tube defect prevention. [PDF]
To assess the knowledge and practice of urban Iranian pregnant women regarding periconceptional folic acid intake for neural tube defect (NTD) prevention.
Golalipour, M.J. +2 more
core
ABSTRACT Aim Guided by the Developmental Origins of Health and Disease framework, maternal nutrition influences perinatal outcomes and lifelong offspring health. This commentary summarizes the pregnant and lactating women's section of Dietary Reference Intakes for Japanese (2025), contextualizes them within current Japanese evidence, and identifies ...
Yoshifumi Kasuga +3 more
wiley +1 more source

