Results 61 to 70 of about 7,547 (198)

Koenigs-Knorr Glycosylation with Neuraminic Acid Derivatives [PDF]

International Journal of Carbohydrate Chemistry, 2010
Earlier we reported a convenient and efficient method of preparing α2-6 sialooligosaccharides in conditions of Koenigs-Knorr reaction. The use of Ag2CO3 allowed carrying out α2-6 sialylation of galacto-4,6-diol of mono- and disaccharides with chloride of acetylated N-acetylneuraminic acid methyl ester as glycosyl donor.
Galina Pazynina, Vitaly Nasonov, Ivan Belyanchikov, Reinchard Brossmer, Maxim Maisel, Alexander Tuzikov, Nicolai Bovin   +6 more
openaire   +1 more source

Differential lectin binding patterns in the oviductal ampulla of the horse during oestrus [PDF]

, 2005
We investigated the oligosaccharide sequence of glycoconjugates, mainly sialoglycoconjugates, in the horse oviductal ampulla during oestrus by means of lectin and pre-lectin methods such as the KOH-neuraminidase procedure to remove sialic acid ...
Acone, Franca, Corriero, Aldo, De Metrio, Gregorio, Deflorio, Michele, Desantis, Salvatore, Palmieri, Giovanni, Ventriglia, Gianluca, Zubani, Dolores   +7 more
core  

Profiling of Glycan Receptors for Minute Virus of Mice in Permissive Cell Lines Towards Understanding the Mechanism of Cell Recognition [PDF]

, 2013
The recognition of sialic acids by two strains of minute virus of mice (MVM), MVMp (prototype) and MVMi (immunosuppressive), is an essential requirement for successful infection.
Agbandje-McKenna, M, Chen, X, Cotmore, S, Cummings, RD, Dell, A, Halder, S, Haslam, SM, Heimburg-Molinaro, J, McKenna, R, North, SJ, Smith, DF, Tattersall, P, Trollope, AJ   +12 more
core   +1 more source

Polysialosides Outperform Sulfated Analogs for Binding with SARS‐CoV‐2

Small, Volume 21, Issue 34, August 28, 2025.
Both sulfated and sialylated glycans present on the cell surface act as co‐receptors for the SARS‐CoV‐2 attachment. Polysialylated and sulfated dendritic polyglycerols are studied for their binding with SARS‐CoV‐2. In solution, dendritic polyglycerol sialosides (dPGSAs) bind significantly stronger (low nm) to SARS‐CoV‐2 than their sulfated analogs ...
Vinod Khatri, Nico Boback, Hassan Abdelwahab, Daniela Niemeyer, Tahlia M. Palmer, Anil Kumar Sahoo, Yannic Kerkhoff, Kai Ludwig, Julian Heinze, Dilara Balci, Jakob Trimpert, Rainer Haag, Tatyana L. Povolotsky, Roland R. Netz, Christian Drosten, Daniel C. Lauster, Sumati Bhatia   +16 more
wiley   +1 more source

Gut Microbiota Composition and Modulation in Developmental and Epileptic Encephalopathies

European Journal of Neuroscience, Volume 62, Issue 4, August 2025.
Clinical studies link gut microbiota (GM) composition to adrenocorticotropic hormone (ACTH) treatment response. In infantile epileptic spasms syndrome (IESS) mouse models, GM modulation via antibiotics, ketogenic diet (KD), fecal transplantation, or probiotics reduced epileptic spasms, while in Dravet syndrome (DS) models, the KD showed no anti‐seizure
Takwa Ammar, Fatma Abdelhedi, Leila Ammar keskes, Chahnez Charfi Triki   +3 more
wiley   +1 more source

Planococcus versutus sp. nov., isolated from soil [PDF]

, 2017
A taxonomic study was performed on a novel Gram-stain-positive, coccus-shaped, orange-pigmented motile bacterium, designated as strain L10.15T. The organism was isolated from a soil sample collected in Lagoon Island (close to Adelaide Island, western ...
Chan, Kok-Gan, Convey, Peter, Ee, Robson, Kwon, Soon-Wo, Lim, Yan Lue, Madhaiyan, Munusamy, Pearce, David, See-Too, Wah-Seng, Tan, Jia Yi, Yin, Wai Fong   +9 more
core   +3 more sources

Safety of lacto‐N‐tetraose (LNT) produced by a derivative strain (Escherichia coli K‐12 MG1655 INB_LNT_01) of E. coli K‐12 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, Volume 23, Issue 8, August 2025.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on lacto‐N‐tetraose (LNT) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human‐identical milk oligosaccharide (HiMO) LNT, but it also contains lacto‐N ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Rosangela Marchelli, Harry J. McArdle, Monika Neuhäuser‐Berthold, Morten Poulsen, Miguel Prieto Maradona, Josef Rudolf Schlatter, Alexandros Siskos, Henk van Loveren, Paolo Colombo, Pablo Rodríguez Fernández, Estefanía Noriega Fernández, Karen Ildico Hirsch‐Ernst   +30 more
wiley   +1 more source

Origin of Neuraminic Acid in Human Seminal Fluid [PDF]

Nature, 1964
THE occurrence and possible function of the neuraminic acids in mammalian tissues and fluids is a matter of great interest. Large amounts of N-acetylneuraminic acid have been demonstrated in the seminal fluid of man1,2, bull3 and boar4. Analysis of the secretions of the accessory genital organs of the boar showed that the mucin from the bulbourethral ...
openaire   +2 more sources

Investigating the Utility of Leukocyte Sialic Acid Measurements in Lysosomal Free Sialic Acid Storage Disorder

JIMD Reports, Volume 66, Issue 4, July 2025.
Schematic illustrating the study design and key findings. Figure created in Biorender.com. ABSTRACT Lysosomal free sialic acid storage disorder (FSASD) is a rare, multisystem neurodegenerative disease caused by biallelic pathogenic variants in SLC17A5, encoding sialin.
Marya S. Sabir, Laura Pollard, Lynne Wolfe, David R. Adams, Carla Ciccone, Petcharat Leoyklang, Frances M. Platt, Marjan Huizing, William A. Gahl, May Christine V. Malicdan   +9 more
wiley   +1 more source

In vitro and in vivo modification of Neisseria gonorrhoeae lipooligosaccharide epitope structure by sialylation. [PDF]

, 1990
After growth of gonococci in the presence of cytidine monophospho-N-acetyl-neuraminic acid (CMP-NANA), their 4.5-kD lipooligosaccharide (LOS) component was increased by approximately 400 daltons, whereas the LOS of strains lacking the 4.5-kD component ...
Apicella, MA, Cole, JA, Griffiss, JM, Lesse, AJ, Mandrell, RE, Morse, SA, Parsons, NJ, Shero, M, Smith, H, Sugai, JV   +9 more
core   +1 more source