Results 41 to 50 of about 4,510 (156)

Origin of Neuraminic Acid in Human Seminal Fluid [PDF]

open access: yesNature, 1964
THE occurrence and possible function of the neuraminic acids in mammalian tissues and fluids is a matter of great interest. Large amounts of N-acetylneuraminic acid have been demonstrated in the seminal fluid of man1,2, bull3 and boar4. Analysis of the secretions of the accessory genital organs of the boar showed that the mucin from the bulbourethral ...
openaire   +2 more sources

Nanomaterial‐Based Optical Biosensors for SARS‐CoV‐2 Detection: A Retrospective of the Pandemic

open access: yesAdvanced Sensor Research, Volume 4, Issue 9, September 2025.
This review discusses nanomaterial‐based optical biosensors developed for or adapted to the detection of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). It concludes by providing a perspective on how lessons learned during the coronavirus disease of 2019 (COVID‐19) pandemic may be applied for future research on nanomaterial‐based ...
Flavie Martin   +2 more
wiley   +1 more source

Neuraminic Acid as a Constituent of Human Cerebrospinal Fluid.

open access: yesExperimental Biology and Medicine, 1956
Conclusions1. The neuraminic acid (NA) content of 49 samples of human cerebrospinal fluid (CSF) was studied. In all instances the quantitative relationship of neuraminic acid to the cerebrospinal fluid protein was far in excess of that prevalent in serum.
M K, RUMLEY, L L, UZMAN
openaire   +2 more sources

Toward the Synthesis of 3,3‐Difluoro Deaminated Sialic Acid (C3DFKDN)

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 30, August 19, 2025.
The synthesis of protected C3‐difluoro KDN (C3DFKDN), an unnatural derivative of the sialic acid member, KDN, and key building block for KDN‐based chemical probes, is reported. Its 12‐step synthetic route starts from commercially available methyl d‐mannopyranoside and key steps include a Reformatsky reaction with ethyl bromodifluoroacetate, alkylation ...
Lemeng Chao, Tom Wennekes
wiley   +1 more source

Polysialosides Outperform Sulfated Analogs for Binding with SARS‐CoV‐2

open access: yesSmall, Volume 21, Issue 34, August 28, 2025.
Both sulfated and sialylated glycans present on the cell surface act as co‐receptors for the SARS‐CoV‐2 attachment. Polysialylated and sulfated dendritic polyglycerols are studied for their binding with SARS‐CoV‐2. In solution, dendritic polyglycerol sialosides (dPGSAs) bind significantly stronger (low nm) to SARS‐CoV‐2 than their sulfated analogs ...
Vinod Khatri   +16 more
wiley   +1 more source

Label‐Free and Microplate‐Based Dissection of Glycan‐Virus Interactions Using Polymer‐Tethered Glyconanoparticles

open access: yesSmall Methods, Volume 9, Issue 8, August 20, 2025.
This work demonstrates the use of polymer‐tethered glycosylated gold nanoparticles for the label‐free evaluation of influenza virus binding in a simple microplate. Sialylated linear and branched glycans are integrated using a modular capture and assembly process. The microplate‐based assays are shown to correlate with biolayer interferometry and can be
Sarah‐Jane Richards   +11 more
wiley   +1 more source

Expanding salivary biomarker detection by creating a synthetic neuraminic acid sensor via chimeragenesis. [PDF]

open access: yesAppl Environ Microbiol
Verzino SJ   +14 more
europepmc   +1 more source

Intestinal mucus acts as a nutrient source and signal for <i>Klebsiella pneumoniae</i>. [PDF]

open access: yesMicrobiome Res Rep
Ticer TD   +8 more
europepmc   +1 more source

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