Results 31 to 40 of about 4,739 (156)

Safety of 3′‐sialyllactose (3′‐SL) sodium salt produced with a derivative strain (Escherichia coli K‐12 MG1655 INB‐3SL_01) of E. coli K‐12 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, Volume 24, Issue 3, March 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 3′‐sialyllactose (3′‐SL) sodium salt as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human‐identical milk oligosaccharide (HiMO) 3′‐SL (sodium salt),
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Thomas Frenzel, Harry J. McArdle, Peter Moldeus, Monika Neuhäuser‐Berthold, Josef Rudolf Schlatter, Henk van Loveren, Estefanía Noriega Fernández, Karen Ildico Hirsch‐Ernst   +23 more
wiley   +1 more source

Harnessing the acceptor substrate promiscuity of Clostridium botulinum Maf glycosyltransferase to glyco-engineer mini-flagellin protein chimeras

Communications Biology
Several bacterial flagellins are O-glycosylated with nonulosonic acids on surface-exposed Serine/Threonine residues by Maf glycosyltransferases. The Clostridium botulinum Maf glycosyltransferase (CbMaf) displays considerable donor substrate promiscuity ...
Sonali Sunsunwal, Aasawari Khairnar, Srikrishna Subramanian, T.N.C. Ramya   +3 more
doaj   +1 more source

Sialic Acid Sensing via Molecularly Imprinted Polymer on Laser‐Induced Graphene

Advanced Sensor Research, Volume 5, Issue 2, February 2026.
Sialic acid is an important biomarker for oral and overall health. Salivary levels of sialic acid are linked with oral cancer and other diseases. We develop a point‐of‐care sensor for sialic acid, based on molecularly imprinted aminophenylboronic acid electropolymerized onto laser‐induced graphene.
Alexander V. Shokurov, Max Nobre Supelnic, Carlo Menon   +2 more
wiley   +1 more source

Antibody‐Targeted Artificial T Cell and Natural Killer Cell Derived Vesicles for Cancer Immunotherapy

Journal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
ABSTRACT T cell and NK92 cell‐derived extracellular vesicles or artificial cell‐derived vesicles (ACDVs) exhibit anti‐cancer effects through inherited cytotoxic proteins like perforin and granzyme or transmembrane receptors like FasL and TRAIL. The anti‐cancer potential of artificial T and NK vesicles has been improved by attaching targeting moieties ...
Brijesh Parlekar, David W. Livingstone, Ashley R. Sutherland, Andrés X. Medina, Wendy Bernhard, John DeCoteau, Tays Hernández, Clarence Ronald Geyer   +7 more
wiley   +1 more source

Many locks to one key: N-acetylneuraminic acid binding to proteins

IUCrJ
Sialic acids play crucial roles in cell surface glycans of both eukaryotic and prokaryotic organisms, mediating various biological processes, including cell–cell interactions, development, immune response, oncogenesis and host–pathogen interactions. This
KanagaVijayan Dhanabalan, YiYang Cheng, Trung Thach, Ramaswamy Subramanian   +3 more
doaj   +1 more source

Separation Methods Affect Glycan Patterns in Extracellular Vesicle Preparations From Canine Osteoblasts and Osteosarcoma Cells

Journal of Extracellular Biology, Volume 5, Issue 2, February 2026.
ABSTRACT Extracellular vesicles (EVs) are nanosized, membrane‐enclosed particles released by cells, facilitating intercellular communication via the transfer of bioactive molecules from producing to recipient cells. EVs are involved in several physiological and pathological processes, including cancer progression.
Daniela Cortes Galvez, Silvio Kau‐Strebinger, Simone Gabner, Ingrid Walter   +3 more
wiley   +1 more source

Intra‐ and Intermolecular Glycosylation of d‐Idopyranosyl and 6‐Deoxy‐d‐ido‐heptopyranosyl Donors: Toward the Repeating Unit of Campylobacter jejuni HS:4c Capsular Polysaccharide

European Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
A comprehensive glycosylation study of diversely protected and activated d‐idopyranosyl and 6‐deoxy‐d‐ido‐heptopyranosyl donors using intra‐ and intermolecular coupling strategies is reported. Intramolecular aglycon delivery afforded 1,2‐cis‐β‐idopyranosides, while intermolecular glycosylation yielded chromatographically separable α‐ and β‐linked ...
Maude Cloutier, Nitish Verma, Ilona Douchez, Charles Gauthier   +3 more
wiley   +1 more source

Isolation of a Protease‐Producing Microbacterium From the Intestinal Tract of Ruditapes philippinarum and Its Probiotic Effects

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Aquatic probiotics are generally recognized as safe and nontoxic live bacterial preparations, primarily sourced from the culturing environment or directly from aquatic organisms. Upon entering the aquatic environment, these probiotics are capable of colonizing both the surface and internal compartments of aquatic organisms, thereby enhancing their ...
Hui Guan, Yaodong Qiu, Mingyue Guan, Sitong Quan, Shang Liu, Yingxu Chen, Haochen Li, Haolin Yu, Lei Fang, Zhongming Huo, Arkadios Dimitroglou   +10 more
wiley   +1 more source

Safety of 6′‐sialyllactose (6′‐SL) sodium salt produced with a derivative strain (Escherichia coli K‐12 MG1655 INB‐6SL_02) of E. coli K‐12 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, Volume 24, Issue 1, January 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 6′‐sialyllactose (6’‐SL) sodium salt as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human‐identical milk oligosaccharide (HiMO) 6’‐SL (sodium salt),
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera‐Gómez, Thomas Frenzel, Harry J. McArdle, Peter Moldeus, Monika Neuhäuser‐Berthold, Josef Rudolf Schlatter, Henk van Loveren, Estefanía Noriega Fernández, Karen Ildico Hirsch‐Ernst   +23 more
wiley   +1 more source

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O‐Glycan Degradation and Pathogenicity in a Potentially Multidrug‐Resistant Clostridium tertium Strain

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Seonghun Kim, Ji Young Kang, Jung‐Sook Lee   +2 more
wiley   +1 more source