Results 11 to 20 of about 4,510 (156)
Development of a C5-Azidoacetamide-Modified 4-Amino-2,3-Difluorosialic Acid Activity-Based Probe for Labeling of Influenza A Neuraminidases. [PDF]
ChembiochemWe report DFSA5Az/DFSA5bio, C5‐azidoacetamide 4‐amino‐2,3‐difluorosialic acid activity‐based probes that trap influenza A viral (IAV) neuraminidases (NA) via a stabilized covalent Tyr‐sialosyl intermediate with hour‐scale reactivation. A bioorthogonal azide enables CuAAC (or one‐step biotin) tagging for activity‐dependent Western‐blot detection at ...
Chao L +6 more
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Frontiers in Microbiology, 2021 Species of genus Shewanella are among the most frequently identified psychrotrophic bacteria. Here, we have studied the cellular properties, growth dynamics, and stress conditions of cold-active Shewanella strain #4, which was previously isolated from ...
Muhammad Suleman Qasim +10 more
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Frontiers in Molecular Biosciences, 2021 Mass spectrometry–based high-sensitivity mapping of terminal glycotopes relies on diagnostic MS2 and/or MS3 ions that can differentiate linkage and define the location of substituents including sulfates.
Huan-Chuan Tseng +7 more
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Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O-Glycan Degradation and Pathogenicity in a Potentially Multidrug-Resistant Clostridium tertium Strain. [PDF]
MicrobiologyopenThe comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Kim S, Kang JY, Lee JS.
europepmc +2 more sources
Sphingolipid composition of human platelets
Journal of Lipid Research, 1973 Total lipid extracts from washed trypsinized human platelets were fractionated into neutral lipids, glycosphingolipids, and phosphclipids by silicic acid chromatography.
Robert V.P. Tao +2 more
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Scientific Reports, 2023 Sialic acids (Sias) are a class of sugar molecules with a parent nine-carbon neuraminic acid, generally present at the ends of carbohydrate chains, either attached to cellular surfaces or as secreted glycoconjugates.
Gerardo N. Guerrero-Flores +6 more
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Comparison of sialic acid content in bovine and buffalo milk and meat
Revista Científica, 2023 Animal-origin food, such as meat and milk, are important sources of sialic acids (SIAs) with relevant implications for human health. Two significant SIAs in mammals are N-acetyl-neuraminic acid (Neu5Ac) and N- glycolylneuraminic acid (Neu-5Gc).
Michela Contò +2 more
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BMC Biotechnology, 2009 Background Two sequential enzymes in the production of sialic acids, N-acetyl-D-glucosamine 2-epimerase (GlcNAc 2-epimerase) and N-acetyl-D-neuraminic acid aldolase (Neu5Ac aldolase), were overexpressed as double-tagged gene fusions.
Cheng Chung-Hsien +5 more
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Post-Glycosylation Modification of Sialic Acid and Its Role in Virus Pathogenesis
Vaccines, 2019 Sialic acids are a family of nine carbon keto-aldononulosonic acids presented at the terminal ends of glycans on cellular membranes. α-Linked sialoglycoconjugates often undergo post-glycosylation modifications, among which O-acetylation of N-acetyl ...
Simon S. Park
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Beilstein Journal of Organic Chemistry, 2010 Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal
Arne Homann +4 more
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