Results 71 to 80 of about 7,655 (179)
Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley +1 more source
Detection of Neuraminidase Activity in Pseudomonas aeruginosa PAO1 [PDF]
Objective(s)Some properties of neuraminidase produced by Pseudomonas aeruginosa PAO1 growth in a defined medium (BHI) were examined and evaluated for its features.Materials and MethodsThe obtained supernatant enzyme of P.
Ciamak Ghazaei +2 more
core
Multiplatform characterization of dynamic changes in breast milk during lactation [PDF]
The multicomponent analysis of human breast milk (BM) by metabolic profiling is a new area of study applied to determining milk composition, and is capable of associating BM composition with maternal characteristics, and subsequent infant health outcomes.
Andreas, Nicholas J. +9 more
core +1 more source
Abstract The qualified presumption of safety (QPS) process was developed to assess the safety of microorganisms used in food and feed chains. During the period covered by this Statement, no new information warranted changes to the status of previously recommended QPS taxonomic units.
EFSA Panel on Biological Hazards (BIOHAZ) +28 more
wiley +1 more source
A structural and functional model for human bone sialoprotein [PDF]
Human bone sialoprotein (BSP) is an essential component of the extracellular matrix of bone. It is thought to be the primary nucleator of hydroxyapatite crystallization, and is known to bind to hydroxyapatite, collagen, and cells.
Durrant, Marcus, Vincent, Kevin
core +1 more source
The tetrasaccharide linkage region of proteoglycans is synthesized through a series of well‐controlled enzymatic reactions in nature. The expression, activity, and substrate profile of these biosynthetic enzymes and the latest development of chemoenzymatic synthesis of linkage region‐bearing glycopeptides are summarized in this review.
Po‐han Lin, Xuefei Huang
wiley +1 more source
Origin of Neuraminic Acid in Human Seminal Fluid [PDF]
THE occurrence and possible function of the neuraminic acids in mammalian tissues and fluids is a matter of great interest. Large amounts of N-acetylneuraminic acid have been demonstrated in the seminal fluid of man1,2, bull3 and boar4. Analysis of the secretions of the accessory genital organs of the boar showed that the mucin from the bulbourethral ...
openaire +2 more sources
Enzymatic introduction of azido‐sialic acid residues to the glycans on exosomes enables a new and efficient approach for exosomal functionalization with various probes, including biotin and fluorophores, by biocompatible click chemistry, thereby facilitating detailed investigations of exosomes, such as their glycan profiles, cellular uptake, etc., and ...
Sayan Kundu +5 more
wiley +1 more source
In vitro and in vivo modification of Neisseria gonorrhoeae lipooligosaccharide epitope structure by sialylation. [PDF]
After growth of gonococci in the presence of cytidine monophospho-N-acetyl-neuraminic acid (CMP-NANA), their 4.5-kD lipooligosaccharide (LOS) component was increased by approximately 400 daltons, whereas the LOS of strains lacking the 4.5-kD component ...
Apicella, MA +9 more
core +1 more source
Combination of automated solid-phase and enzymatic oligosaccharide synthesis provides access to α(2,3)-sialylated glycans [PDF]
A synthetic strategy combining automated solid-phase chemical synthesis and enzymatic sialylation was developed to access α(2,3)-sialylated glycans.
Fair, Richard J. +2 more
core +1 more source

