Glycans in melanoma: Drivers of tumour progression but sweet targets to exploit for immunotherapy
Immunology, Volume 173, Issue 1, Page 33-52, September 2024.Aberrant glycosylation patterns on tumour cells emerged as an unmissable hallmark of cancer progression. Such tumour ‘glycocode’ plays a major role in promoting tumour cell proliferation, invasion, migration, but also dismantles anti‐tumour defences through interactions with lectins expressed on immune cells.
Camille Niveau +3 more
wiley +1 more source
LC/ESI-MS analysis of underivatized amino acids and mass spectrum [PDF]
arXiv, 2016 We report the method of LC/ESI-MS analysis of underivatized amino acids with corresponding mass spectrum and fragmentation patterns. Diagnostic product ions determined by mass spectrometry can support the qualitative identification and quantitative estimation of individual amino acids. Therefore, the optimization of chromatographic separation using the
arxiv
Correlations of Amino Acids with Secondary Structure Types: Connection with Amino Acid Structure [PDF]
arXiv, 2005 The correlations of primary and secondary structures were analyzed using proteins with known structure from Protein Data Bank. The correlation values of amino acid type and the eight secondary structure types at distant position were calculated for distances between -25 and 25.
arxiv
Boric Acid Catalyzed Methyl Esterification of Sugar Acids
, 2014 Boric acid catalyzes methyl esterification of certain sugar acids (sialic acid, deaminated neuraminic acid) and related natural products (quinic acid) quite cleanly in some cases. However, closely related sugar acids (glucuronic acid, 3-deoxy-d-manno-oct-
Stephan M Levonis +4 more
semanticscholar +1 more source
Glycobiology, 1992 Historical background It is now more than 50 years since N-acetyl-neuraminic acid was first discovered and subsequently characterized by several groups (reviewed in Roseman, 1970; Gottschalk, 1972; Rosenberg and Schengrund, 1976; Schauer, 1982; Faillard,
A. Varki
semanticscholar +1 more source
Linguistic mechanism of the evolution of amino acid frequencies and genomic GC content [PDF]
arXiv, 2006 Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code determines the evolution of amino acid frequencies and genomic GC content.
arxiv
Genetic Code Table: A note on the three splittings into amino acid classes [PDF]
arXiv, 2009 This note represents the further progress in understanding the determination of the genetic code by Golden mean (Rakocevic, 1998). Three classes of amino acids that follow from this determination (the 7 "golden" amino acids, 7 of their complements, and 6 non-complements) are observed now together with two further possible splittings into 4 x 5 and 5 x ...
arxiv
Role of neuraminic acid in the heterogeneity of alkaline phosphatase in sheep brain [PDF]
, 1968 S. Saraswathi, B.K. Bachhawat
openalex +1 more source
Indigenous amino acids in primitive CR meteorites [PDF]
arXiv, 2008 CR meteorites are among the most primitive meteorites. In this paper, we report the first measurements of amino acids in Antarctic CR meteorites, two of which show the highest amino acid concentrations ever found in a chondrite. EET92042, GRA95229 and GRO95577 were analyzed for their amino acid content using high performance liquid chromatography with ...
arxiv
On the specificity of neuraminidase The carboxymethyl α‐ketoside of N‐acetyl‐D‐neuraminic acid, aVibrio cholerae neuraminidase substrate having two anionic sites [PDF]
, 1972 Leif Holmquist, Reinhard Brossmer
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