Results 121 to 130 of about 48,869 (270)
ABSTRACT Backgrounds The antiviral drug prescription landscape has changed as new antivirals for influenza treatment have been approved. Understanding this landscape is important to assess potential under‐ and mis‐utilization and to address gaps in care.
Kyueun Lee +2 more
wiley +1 more source
Influenza treatment and prophylaxis with neuraminidase inhibitors: a review
Amanda Kamali,1 Mark Holodniy1,21Division of Infectious Diseases, Stanford University School of Medicine, Stanford, CA, USA; 2Office of Public Health, Department of Veterans Affairs, Washington, DC, USAAbstract: Influenza virus is a pathogen that causes ...
Kamali A, Holodniy M
core
Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children
BACKGROUND: Neuraminidase inhibitors (NIs) are stockpiled and recommended by public health agencies for treating and preventing seasonal and pandemic influenza. They are used clinically worldwide.
T. Jefferson +6 more
semanticscholar +1 more source
ABSTRACT Background Influenza causes 650,000 deaths, 3–5 million hospitalizations, and 1 billion cases worldwide each year. There is a limited repertoire of antivirals available to tackle this burden, highlighting the risk of developing resistance to current drugs.
Alejandro Martín‐Toribio +15 more
wiley +1 more source
Neuraminidase-1: A novel therapeutic target in multistage tumorigenesis
Several of the growth factors and their receptor tyrosine kinases (RTK) such as epidermal growth factor (EGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), vascular endothelial growth factor (VEGF), nerve growth factor (NGF) and
Fiona Haxho, R. Neufeld, M. Szewczuk
semanticscholar +1 more source
Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase
This work was supported by the Medical Research Council and the Scottish Funding Council.Influenza virus sialidase has an essential role in the virus’ life cycle.
Russell, Rupert James Martin +9 more
core +1 more source
Complete analysis of the H5 hemagglutinin and N8 neuraminidase phylogenetic trees reveals that the H5N8 subtype has been produced by multiple reassortment events [PDF]
The analysis of the complete H5 hemagglutinin and H8 neuraminidase phylogenetic trees presented in this paper shows that the H5N8 avian influenza has been generated by multiple reassortment events.
Dalby, A.R.
core +1 more source
Influenza B viruses are antigenically diverse and contribute significantly to the annual influenza burden. Here we report influenza B virus neutralizing single-domain antibodies that target highly conserved regions of the hemagglutinin and neuraminidase.
Arne Matthys +9 more
doaj +1 more source
The lectin neuraminidase (LN) test is based on specific interaction between Arachis lectin and the glycoprotein receptors treated with the neuraminidase (NA) of myxoviruses. The test is suitable for detection of mumps virus NA and of corresponding antibodies and is more sensitive than the conventional neuraminidase inhibition test.
P, Luther, H, Klamm, S, Weber
openaire +1 more source
Four World Health Organization (WHO) Collaborating Centres for Reference and Research on Influenza and one WHO Collaborating Centre for the Surveillance, Epidemiology and Control of Influenza (WHO CCs) tested 10,641 viruses collected by WHO-recognized ...
E. Takashita +18 more
semanticscholar +1 more source

