Results 111 to 120 of about 52,033 (201)
VaccinesBackground: Polypeptide vaccines have the potential to improve immune responses by targeting conserved and weakly immunogenic regions in antigens. This study aimed to identify and evaluate the efficacy of a novel influenza universal vaccine candidate ...
Song Zhao +7 more
doaj +1 more source
Decoding neurodevelopment risks of exposures to intoxication, infection, and trauma during pregnancy
Pregnancy, Volume 2, Issue 5, September 2026.Abstract The maternal environment plays a pivotal role in fetal neurodevelopment, but adverse conditions during pregnancy may disrupt key developmental processes. Conditions such as intoxication, infection, or trauma during pregnancy have been associated with impaired fetal oxygenation, altered immune signaling, and disrupted placental function, which ...
Brenda E. Lujan +7 more
wiley +1 more source
ChemistrySelect, Volume 11, Issue 33, 1 September 2026.This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira +8 more
wiley +1 more source
Wildlife Monographs, Volume 225, Issue 1, September 2026.We describe the host response continuum for highly pathogenic avian influenza viruses (HPAIV), including the continuum of host responses to HPAIV infection and exposure based on the primary axis of host competence, ability to infect other hosts, and host vulnerability.
Johanna A. Harvey +9 more
wiley +1 more source
Neuraminidase production by clostridia
, 1978 THE assay for neuraminidase (EC 3.2.1.18) developed by Fraser and ...
A. G. Fraser
core +1 more source
Some Exposure for Influenza Hemagglutinin Interface Antibodies
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT Influenza viruses are a constant threat to human health. Current vaccines often confer low to moderate protection against infection with seasonal viruses and little‐to‐no protection against pandemic viruses. Improved vaccines are needed. These vaccines will need to reliably elicit antibodies to conserved sites that are broadly protective.
Kevin R. McCarthy
wiley +1 more source
Immunological Reviews, Volume 342, Issue 1, September 2026.ABSTRACT Human infection with or vaccination against influenza A virus has been one of the most informative systems for understanding how human antibody repertoires recognize viral glycoproteins. Decades of antibody isolation, repertoire sequencing, lineage tracing, serology, viral antigenic evolution, and structural biology have shown that antibody ...
Bruno Bonnettaz, Goran Bajic
wiley +1 more source
Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.ABSTRACT Background H5Nx goose/Guangdong (Gs/GD) lineage highly pathogenic avian influenza (HPAI) viruses pose a significant public health threat due to their global spread, mutation accumulation, and expanding host range. The descendant clade 2.3.4.4b has been causing widespread infections in birds and increasing spillover events in mammals.
Giulia D'Annunzio +29 more
wiley +1 more source
, 2010 [[abstract]]Scutellaria baicalensis Georgi is often included as an ingredient in traditional Chinese compound prescriptions for the treatment of fever-related or inflammatory conditions.
Yen-Kuan Lin
core
Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.ABSTRACT The emergence of viruses with reduced susceptibility to antivirals poses an ongoing risk which could limit their effectiveness. Here we report a cluster of A(H3N2) viruses detected in Tasmania, Australia, with a PA gene mutation A37T that showed mild reductions in susceptibility in vitro to baloxavir (3.47‐ to 16.33‐fold increased EC50) when ...
Saira Hussain +14 more
wiley +1 more source