Results 111 to 120 of about 48,869 (270)

The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency

Clinical Genetics, Volume 110, Issue 1, Page 125-130, July 2026.
We identify a female patient with a homozygous nonsense variant (p.Gln38Ter) in the LYSET gene. This is the first western report of a challenging case of an extensive diagnostic odyssey and demonstrates that the LYSET gene must be considered in the differential diagnosis when M6P‐labeled lysosomal enzymes are altered.
Fernanda Sperb‐Ludwig, Taciane Alegra, Leonardo Martinello da Rosa, Nataniel Floriano Ludwig, Renata Voltolini Velho, Ida Vanessa Doederlein Schwartz   +5 more
wiley   +1 more source

Contemporary disasters may not kill more women than men: an empirical inquiry into sex‐differentiated fatalities in the twenty‐first century

Disasters, Volume 50, Issue 3, July 2026.
Abstract This study investigates the claim that women are disproportionately more likely to die in disasters by reviewing existing data sources and compiling new datasets on sex‐differentiated disaster fatalities in the twenty‐first century. The analysis is structured by disaster type, covering geophysical, meteorological, climatological, hydrological,
Olivier Rubin
wiley   +1 more source

Discovering Neuraminidase Inhibitors via Computational and Experimental Studies

Influenza A viruses spread out worldwide causing several global concerns. Discovering neuraminidase inhibitors to prevent the influenza A virus is thus of great interests.
Son Tung, Ngo, Ngoc Quynh Anh, Pham, Trung Hai, Nguyen, Quynh Mai, Thai, Van V., Van, Jim-Tong, Horng   +5 more
core   +1 more source

Neuraminidase-Inhibiting Antibody Titers Correlate with Protection from Heterologous Influenza Virus Strains of the Same Neuraminidase Subtype.

, 2018
Immune responses induced by currently licensed inactivated influenza vaccines are mainly directed against the hemagglutinin (HA) glycoprotein, the immunodominant antigen of influenza viruses. The resulting antigenic drift of HA requires frequent updating
Zimmer, Gert, Walz, Lisa, Gert Zimmer, Kays, Sarah-Katharina, Lisa Walz, Veronika von Messling, Sarah-Katharina Kays, von Messling, Veronika   +7 more
core   +1 more source

Oseltamivir-Resistant Influenza A(H1N1)pdm09 Viruses, United States, 2013–14

Emerging Infectious Diseases, 2015
We report characteristics of oseltamivir-resistant influenza A(H1N1)pdm09 viruses and patients infected with these viruses in the United States.
Margaret Okomo-Adhiambo, Alicia Fry, Su Su, Ha T. Nguyen, Anwar Abd Elal, Elizabeth Negron, Julie Hand, Rebecca J. Garten, John Barnes, Xu Xiyan, Julie M. Villanueva, Larisa Gubareva   +11 more
doaj   +1 more source

Navigating the Future of Respiratory Infections: Key Insights From International Congress in Singapore, 17–20 September 2025

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background The 8th International Society for Respiratory Viruses (ISRV) Antiviral Group Conference, held jointly with the 3rd International Meeting on Respiratory Pathogens in Singapore (17–20 September 2025), examined evolving approaches to prevention and management of respiratory infections.
Narmadha Morvil, Wilson Guo Wei Goh, Charlotte Zheng, Stephanie Sutjipto, Dorothy Hui Lin Ng, Maria Zambon   +5 more
wiley   +1 more source

Preliminary crystallographic data for influenza virus neuraminidase "heads"

, 1978
Neuraminidase “heads” released by Pronase digestion from particles of a recombinant influenza virus (A/NWSHA—Tokyo/3/67NA, HON2) have been purified and crystallised.
Laver, W.G., Wright, Carolyn E., Laver, W. G.   +2 more
core   +1 more source

Immunogenicity of a Multi‐Epitope Influenza Composite Peptide Vaccine Targeting Human, Swine, and Avian Viruses: Advancing Pandemic Preparedness

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background The emergence of novel reassortant influenza A virus strains and zoonotic transmission to the human population is a critical factor in the development of a global pandemic, as exemplified by the 2009 swine flu pandemic and the ongoing threat of an H5N1 avian flu pandemic.
Nimisha Rikhi, Clara J. Sei, Kellie A. Fraser, Kevin Muema, Aba Assiaw‐Dufu, Richard F. Schuman, Gerald W. Fischer   +6 more
wiley   +1 more source

Exploration of the 150 Cavity and the Role of Serendipity in the Discovery of Inhibitors of Influenza Virus A Neuraminidase

, 2017
Influenza pandemics are an on-going threat for the human population as the avian influenza viruses H5N1 and H7N9 continue to circulate in the bird population and the chance of avian to human transmission increases.
Sankar Mohan, Pinto, Mario BM, Pinto, B Mario, B. Mario Pinto, Mohan, Sankar   +4 more
core   +1 more source

Microsecond Molecular Dynamics Simulations of Influenza Neuraminidase Suggest a Mechanism for the Increased Virulence of Stalk-Deletion Mutants

Journal of Physical Chemistry B, 2016
Deletions in the stalk of the influenza neuraminidase (NA) surface protein are associated with increased virulence, but the mechanisms responsible for this enhanced virulence are unclear.
Jacob D. Durrant, R. Bush, Rommie E. Amaro   +2 more
semanticscholar   +1 more source