Results 131 to 140 of about 48,869 (270)

Novel Anti-Viral Properties of the Herbal Extract of Davallia mariesii against Influenza A Virus

Viruses
Gu-Sui-Bu, the dried rhizome of Davallia mariesii, is a traditional Chinese herbal remedy with a significant history of treating osteoporosis and inflammatory conditions.
Yu-Li Chen, Pei-Yu Chao, Chung-Fan Hsieh, Pei-Wen Hsieh, Jim-Tong Horng   +4 more
doaj   +1 more source

Hemagglutinin–Neuraminidase of Human Parainfluenza 3: Role of the Neuraminidase in the Viral Life Cycle

, 1995
The function of neuraminidase in the life cycle and pathogenesis of human parainfluenza virus type 3 (HPF3) was studied by analyzing a variant of HPF3 that has decreased neuraminidase enzymatic activity.
HUBERMAN, KETY, MOSCONA, ANNE, PELUSO, RICHARD W.   +2 more
core   +1 more source

Monitoring and Characterization of Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, Japan, 2009–2010

Emerging Infectious Diseases, 2011
To monitor and characterize oseltamivir-resistant (OR) pandemic (H1N1) 2009 virus with the H275Y mutation, we analyzed 4,307 clinical specimens from Japan by neuraminidase (NA) sequencing or inhibition assay; 61 OR pandemic (H1N1) 2009 viruses were ...
Makoto Ujike, Miho Ejima, Akane Anraku, Kozue Shimabukuro, Masatsugu Obuchi, Noriko Kishida, Xu Hong, Emi Takashita, Seiichiro Fujisaki, Kazuyo Yamashita, Hiroshi Horikawa, Yumiko Kato, Akio Oguchi, Nobuyuki Fujita, Masato Tashiro, Takato Odagiri   +15 more
doaj   +1 more source

Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers

Nature Communications, 2015
A(H1N1)pdm09 influenza A viruses predominated in the 2013–2014 USA influenza season, and although most of these viruses remain sensitive to Food and Drug Administration-approved neuraminidase (NA) inhibitors, alternative therapies are needed.
H. Wan, Hua Yang, D. Shore, R. Garten, Laura K. Couzens, Jin Gao, Lianlian Jiang, P. Carney, J. Villanueva, J. Stevens, M. Eichelberger   +10 more
semanticscholar   +1 more source

neuraminidase trees global xml

, 2014
BEAST xml file used to generate neuraminidase trees for global analysis (a single ...
Trevor Bedford (376961), Robert J. Woods (175743), Mercedes Pascual (19597), Edward B. Baskerville (189872), Manojit Roy (104218), Daniel Zinder (106377)   +5 more
core   +1 more source

Influenza a Neuraminidase-Based Bivalent mRNA Vaccine Induces Th1-Type Immune Response and Provides Protective Effects in Mice

Vaccines
Vaccines are one of the most effective means of preventing influenza A, typically containing the hemagglutinin (HA) of the influenza A virus. However, antigenic drift and shift of the influenza A virus can lead to instability in vaccine efficacy ...
Mingyang Li, Mengyuan Liu, Shaohui Song, Ruirui Zhao, Yun Xie, Jing Liu, Lilan Xu, Xuefeng Ma, Mingyu Song, Jian Zhou, Guoyang Liao   +10 more
doaj   +1 more source

Influenzavirus neuraminidase and neuraminidase-inhibition test procedures.

Bulletin of the World Health Organization, 1973
The adequate characterization of type A influenzaviruses requires the identification not only of the haemagglutinin but also of the neuraminidase. The neuraminidase-inhibition test, as performed in the two WHO international reference centres for influenza, is described and its use in other laboratories-particularly those collaborating in the WHO ...
M, Aymard-Henry, M T, Coleman, W R, Dowdle, W G, Laver, G C, Schild, R G, Webster   +5 more
openaire   +1 more source

The Development of a Novel Broad-Spectrum Influenza Polypeptide Vaccine Based on Multi-Epitope Tandem Sequences

Vaccines
Background: Polypeptide vaccines have the potential to improve immune responses by targeting conserved and weakly immunogenic regions in antigens. This study aimed to identify and evaluate the efficacy of a novel influenza universal vaccine candidate ...
Song Zhao, Junhao Luo, Wenhui Guo, Li Li, Siyu Pu, Libo Dong, Wenfei Zhu, Rongbao Gao   +7 more
doaj   +1 more source

neuraminidase trees NA/OT

, 2014
Neuraminidase trees generated by BEAST for NA/OT analysis in NEXUS ...
Trevor Bedford (376961), Robert J. Woods (175743), Mercedes Pascual (19597), Edward B. Baskerville (189872), Zinder, Daniel, Baskerville, Edward B., Woods, Robert J., Roy, Manojit, Manojit Roy (104218), Bedford, Trevor, Pascual, Mercedes, Daniel Zinder (106377)   +11 more
core   +1 more source

Selective modification of Sendai virus hemagglutinin neuraminidase by pyridoxal 5'-phosphate: evidence for an allosteric modulation of neuraminidase activity

, 1993
Incubation of Sendai virus with pyridoxal 5'-phosphate (PLP) causes inhibition of hemolytic activity, a slight reduction of hemagglutinating activity, and an increase in neuraminidase activity.
Tomasi M., BELLINI, Tiziana, DALLOCCHIO, Franco Pasquale Filippo   +2 more
core   +1 more source