Results 41 to 50 of about 38,379 (201)

A Cross-Reactive Monoclonal Antibody Against Neuraminidases of Both H9N2 and H3N2 Influenza Viruses Shows Protection in Mice Challenging Models

Frontiers in Microbiology, 2021
Neuraminidases (NAs) of H9N2 avian influenza virus (AIV) and H3N2 human seasonal influenza virus (HSIV) share similar antigenic structures. However, there are few reports on epitopes shared by these two NAs.
Fei Wang, Fei Wang, Zhimin Wan, Zhimin Wan, Zhimin Wan, Jinsen Wu, Jinsen Wu, Yajuan Wang, Yajuan Wang, Hui Fu, Hui Fu, Hongxia Shao, Hongxia Shao, Hongxia Shao, Kun Qian, Kun Qian, Kun Qian, Wei Gao, Wei Gao, Wei Gao, Jianqiang Ye, Jianqiang Ye, Jianqiang Ye, Aijian Qin, Aijian Qin, Aijian Qin   +25 more
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

Emerging Infectious Diseases, 2019
We identified an influenza B isolate harboring a Gly407Ser neuraminidase substitution in an immunocompromised patient in Canada before antiviral therapy.
Yacine Abed, Clément Fage, Patrick Lagüe, Julie Carbonneau, Jesse Papenburg, Donald C. Vinh, Guy Boivin   +6 more
doaj   +1 more source

Sialidosis type I: How to alleviate disabling myoclonic seizures?—A multicenter analysis of eight cases and review of the literature

Epilepsia Open, EarlyView.
Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat, I‐Chun Lee, Marica Rubino, Vehap Topçu, Melissa Chavez‐Castillo, Shao Ching Tu, Marwan Shinawi, Isabel Alfradique‐Dunham, Manouela Valtcheva, Astrid Adarmes‐Gómez, Daniel Macias‐Garcia, Laura Laura Muñoz‐Delgado, Silvia Jesús, Pablo Mir, Andreas Merkenschlager, Antonietta Coppola   +15 more
wiley   +1 more source

Detection of Neuraminidase Activity in Pseudomonas aeruginosa PAO1 [PDF]

Iranian Journal of Basic Medical Sciences, 2010
Objective(s)Some properties of neuraminidase produced by Pseudomonas aeruginosa PAO1 growth in a defined medium (BHI) were examined and evaluated for its features.Materials and MethodsThe obtained supernatant enzyme of P.
Ciamak Ghazaei, Malahat Ahmadi, Nima Hosseini Jazani   +2 more
doaj  

Characterization of H5N1 influenza A virus that caused the first highly pathogenic avian influenza outbreak in Saudi Arabia

Journal of Infection in Developing Countries, 2015
Introduction: Saudi Arabia (SA) experienced a highly pathogenic avian influenza (HPAI) H5N1 outbreak in domesticated birds in 2007. Methodology: Forty-three hemagglutinin (HA) and 41 neuraminidase (NA) genes of HPAI H5N1 viruses were sequenced and ...
Ahmed Ali Al-Qahtani, Muhammad Mubin, Fahad N. Almajhdi, Saud Alarifi, Damian M. dela Cruz, Muhammad Shah Nawaz ul Rehman, Mahmoud Moussa Ismail, Nisar Ahmed, Mohamed H. Al-Blowi, Hanif Khalak, Mohammed N. Al-Ahdal   +10 more
doaj   +1 more source

Multiple Neuraminidase Containing Influenza Virus-like Particle Vaccines Protect Mice from Avian and Human Influenza Virus Infection

Viruses, 2022
Avian influenza virus remains a threat for humans, and vaccines preventing both avian and human influenza virus infections are needed. Since virus-like particles (VLPs) expressing single neuraminidase (NA) subtype elicited limited heterosubtypic ...
Hae-Ji Kang, Ki-Back Chu, Keon-Woong Yoon, Gi-Deok Eom, Jie Mao, Min-Ju Kim, Su-Hwa Lee, Eun-Kyung Moon, Fu-Shi Quan   +8 more
doaj   +1 more source

What happened after the epidemic? Equine influenza surveillance sheds light on sources and seasonal risk in the United Kingdom

Equine Veterinary Journal, EarlyView.
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock, John Grewar, Richard Newton   +2 more
wiley   +1 more source

Peripheral nerve repair: a hot spot analysis on treatment methods from 2010 to 2014

Neural Regeneration Research, 2015
Therapeutic strategies for neurological deficits and for promoting nerve regeneration after peripheral nerve injuries have received much focus in clinical research.
Guang-yao Liu, Yan Jin, Qiao Zhang, Rui Li   +3 more
doaj   +1 more source

Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design

Molecules, 2021
As a member of the Orthomyxoviridae family of viruses, influenza viruses (IVs) are known causative agents of respiratory infection in vertebrates. They remain a major global threat responsible for the most virulent diseases and global pandemics in humans.
Sphamadla E. Mtambo, Daniel G. Amoako, Anou M. Somboro, Clement Agoni, Monsurat M. Lawal, Nelisiwe S. Gumede, Rene B. Khan, Hezekiel M. Kumalo   +7 more
doaj   +1 more source