Results 21 to 30 of about 53,295 (182)
Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK [PDF]
, 1995 The sequence variation in a 934 base-pair region of the gene encoding the haemagglutinin-neuraminidase of five human parainfluenza virus type 3 (HPIV3) isolates was determined together with that of a prototype UK strain. All of the clinical isolates were
Easton, A. J. (Andrew J.) +3 more
core +1 more source
, 2023 Influenza, as one of the most serious communicable respiratory infectious diseases, is caused by influenza viruses. Neuraminidase (NA), also referred to as sialidase, is an important protein on the influenza virus surface.
Sheng Zeng (235606) +7 more
core +1 more source
Mucosal Immunity against Neuraminidase Prevents Influenza B Virus Transmission in Guinea Pigs
mBio, 2019 Despite efforts to control influenza virus infection and transmission, influenza viruses still cause significant morbidity and mortality in the global human population each year.
Meagan McMahon +5 more
doaj +1 more source
Economics of neuraminidase inhibitor stock piling for pandemic influenza, Singapore. [PDF]
, 2006 We compared strategies for stock piling neuraminidase inhibitors to treat and prevent influenza in Singapore. Cost-benefit and cost-effectiveness analyses, with Monte Carlo simulations, were used to determine economic outcomes. A pandemic in a population
Stefan Ma +13 more
core +1 more source
A computational-experimental approach identifies mutations that enhance surface expression of an oseltamivir-resistant influenza neuraminidase. [PDF]
PLoS ONE, 2011 The His274→Tyr (H274Y) oseltamivir (Tamiflu) resistance mutation causes a substantial decrease in the total levels of surface-expressed neuraminidase protein and activity in early isolates of human seasonal H1N1 influenza, and in the swine-origin ...
Jesse D Bloom +2 more
doaj +1 more source
Scientific Reports, 2018 Both influenza viral hemagglutinin and neuraminidase can induce protective immune responses in humans. Although the viral hemagglutinin antigens have been quantified in influenza vaccines, the amounts of neuraminidase remain undetermined.
Kangwei Xu +7 more
doaj +1 more source
NAction! How Can Neuraminidase-Based Immunity Contribute to Better Influenza Virus Vaccines?
mBio, 2018 Neuraminidase is one of the two surface glycoproteins of influenza A and B viruses. It has enzymatic activity that cleaves terminal sialic acid from glycans, and that activity is essential at several points in the virus life cycle. While neuraminidase is
Florian Krammer +9 more
doaj +1 more source
Homology modelling and insilico analysis of neuraminidase protein in H1N1 Influenza A virus
Brazilian Archives of Biology and Technology, 2011 In this work, modelling of Neuraminidase protein of Influenza A virus (A/Himeji/1/2009(H1N1)) neuraminidase (NA) protein was done using Modeller 9V2.
Abhilash Manohar
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 1994 Six clinical isolates of influenza A viruses were examined for hemagglutinin receptor specificity and neuraminidase substrate specificity. All of the viral isolates minimally passaged in mammalian cells demonstrated preferential agglutination of human ...
J. N. S. S. Couceiro, L. G. Baum
doaj +1 more source
Microglia activated by microbial neuraminidase contributes to ependymal cell death
Fluids and Barriers of the CNS, 2021 The administration of microbial neuraminidase into the brain ventricular cavities of rodents represents a model of acute aseptic neuroinflammation. Ependymal cell death and hydrocephalus are unique features of this model.
María del Mar Fernández-Arjona +3 more
doaj +1 more source