Results 41 to 50 of about 48,869 (270)
Viruses, 2023 Influenza B virus (IBV) contributes to substantial influenza-mediated morbidity and mortality, particularly among children. Similar to influenza A viruses (IAV), the hemagglutinin (HA) and neuraminidase (NA) of IBV undergo antigenic drift, necessitating ...
Ahmed M. Khalil +5 more
doaj +1 more source
Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Martyna, Agnieszka, Rossman, Jeremy S.
core +1 more source
Scientific Reports, 2017 Lonicera japonica Thunb, rich in chlorogenic acid (CHA), is used for viral upper respiratory tract infection treatment caused by influenza virus, parainfluenza virus, and respiratory syncytial virus, ect in China.
Yue Ding +5 more
semanticscholar +1 more source
Molecules, 2016 Objective: To screen for influenza virus neuraminidase inhibition and to provide a reference for the clinical treatment of influenza using traditional Chinese medicines (TCM).
Xian-Ying Yang +4 more
doaj +1 more source
, 2001 The terminal globular domain of the paramyxovirus hemagglutinin-neuraminidase (HN) glycoprotein spike has a number of conserved residues that are predicted to form its neuraminidase (NA) active site, by analogy to the influenza virus neuraminidase ...
Paul J. Mahon +13 more
core +1 more source
Neuraminidase construction and function
, 2022 Neuraminidase has been of interest for many years as a potential candidate for a universal influenza vaccine. This is due to the limited mutation on the head domain of the protein, specifically the active site where the enzyme lies.
Tucker, Joseph
core +1 more source
Nature Microbiology, 2019 A(H3N2) virus predominated recent influenza seasons, which has resulted in the rigorous investigation of haemagglutinin, but whether neuraminidase (NA) has undergone antigenic change and contributed to the predominance of A(H3N2) virus is unknown.
H. Wan +23 more
semanticscholar +1 more source
R292K Substitution and Drug Susceptibility of Influenza A(H7N9) Viruses
Emerging Infectious Diseases, 2013 Neuraminidase inhibitors are the only licensed antiviral medications available to treat avian influenza A(H7N9) virus infections in humans. According to a neuraminidase inhibition assay, an R292K substitution reduced antiviral efficacy of inhibitors ...
Katrina Sleeman +5 more
doaj +1 more source
Influenza and Other Respiratory Viruses, 2011 Please cite this paper as: Air. (2012) Influenza neuraminidase. Influenza and Other Respiratory Viruses 6(4), 245–256.Influenza neuraminidase is the target of two licensed antivirals that have been very successful, with several more in development. However, neuraminidase has been largely ignored as a vaccine target despite evidence that inclusion of ...
openaire +3 more sources
The Interplay between the Host Receptor and Influenza Virus Hemagglutinin and Neuraminidase
International Journal of Molecular Sciences, 2017 The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of influenza A virus are responsible for the surface interactions of the virion with the host.
Lauren Byrd-Leotis +2 more
semanticscholar +1 more source