Results 51 to 60 of about 52,033 (201)

Inherent Serum Inhibition of Influenza Virus Neuraminidases

Frontiers in Veterinary Science, 2021
Influenza virus vaccines have been designed for human and veterinary medicine. The development for broadly protective influenza virus vaccines has propelled the vaccine field to investigate and include neuraminidase (NA) components into new vaccine ...
Amanda L. Skarlupka, Ted M. Ross, Ted M. Ross   +2 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Neuraminidase inhibitors protect the glycocalyx.

, 2022
Representative images and comparison of glycocalyx staining intensity in human umbilical vein endothelial cells shows that glycocalyx staining intensity is preserved when neuraminidase exposure occurs in the presence of the neuraminidase inhibitor ...
Olan Jackson-Weaver (11512962), Chad Steele (13079), Sarah Abdullah (11512965), Juan Duchesne (11512980), Derek Pociask (11512983), Farhana Shaheen (3209685), Lauren Mueller (13982850), Brennan Gagen (8359209), Sharven Taghavi (11512959), Jay Kolls (11512986)   +9 more
core   +1 more source

Beyond the Biological Effect of a Chemically Characterized Poplar Propolis: Antibacterial and Antiviral Activity and Comparison with Flurbiprofen in Cytokines Release by LPS-Stimulated Human Mononuclear Cells

Biomedicines, 2019
Bee propolis, especially Euro-Asian poplar propolis, is among the most well-known natural products traditionally used to treat pharyngitis and minor wounds. The aim of this research was to investigate the pharmacological properties responsible for poplar
Paolo Governa, Maria Grazia Cusi, Vittoria Borgonetti, José Mauricio Sforcin, Chiara Terrosi, Giulia Baini, Elisabetta Miraldi, Marco Biagi   +7 more
doaj   +1 more source

A Cross-Reactive Monoclonal Antibody Against Neuraminidases of Both H9N2 and H3N2 Influenza Viruses Shows Protection in Mice Challenging Models

Frontiers in Microbiology, 2021
Neuraminidases (NAs) of H9N2 avian influenza virus (AIV) and H3N2 human seasonal influenza virus (HSIV) share similar antigenic structures. However, there are few reports on epitopes shared by these two NAs.
Fei Wang, Fei Wang, Zhimin Wan, Zhimin Wan, Zhimin Wan, Jinsen Wu, Jinsen Wu, Yajuan Wang, Yajuan Wang, Hui Fu, Hui Fu, Hongxia Shao, Hongxia Shao, Hongxia Shao, Kun Qian, Kun Qian, Kun Qian, Wei Gao, Wei Gao, Wei Gao, Jianqiang Ye, Jianqiang Ye, Jianqiang Ye, Aijian Qin, Aijian Qin, Aijian Qin   +25 more
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Exploration of the 150 Cavity and the Role of Serendipity in the Discovery of Inhibitors of Influenza Virus A Neuraminidase [PDF]

, 2017
Influenza pandemics are an on-going threat for the human population as the avian influenza viruses H5N1 and H7N9 continue to circulate in the bird population and the chance of avian to human transmission increases.
Sankar Mohan, Pinto, Mario BM, Pinto, B Mario, B. Mario Pinto, Mohan, Sankar   +4 more
core   +1 more source

Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

Emerging Infectious Diseases, 2019
We identified an influenza B isolate harboring a Gly407Ser neuraminidase substitution in an immunocompromised patient in Canada before antiviral therapy.
Yacine Abed, Clément Fage, Patrick Lagüe, Julie Carbonneau, Jesse Papenburg, Donald C. Vinh, Guy Boivin   +6 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Supplementary Material for: ‘a’-Position-Mutated and G4-Mutated Hemagglutinin-Neuraminidase Proteins of Newcastle Disease Virus Impair Fusion and Hemagglutinin-Neuraminidase-Fusion Interaction by Different Mechanisms

, 2017
Objectives: To determine the effects of heptad repeat regions (HRs) and N-linked carbohydrate sites of the Newcastle disease virus hemagglutinin-neuraminidase (HN) protein on fusion of HN and fusion (F) proteins and HN-F interaction.
Zhang W. (2888090), Chu F. (4134397), Wen H. (4134403), Sun C. (4052647), Wang Z. (2888096), Ren G. (4052971), Song Y. (3137490), Lin B. (4134400), Zhang Y. (2828780)   +8 more
core   +1 more source