Analysis of the Role of N-Linked Glycans on Human CD1d Molecules. [PDF]
ABSTRACT CD1d is a cell‐surface expressed glycoprotein that presents a variety of lipid and glycolipid antigens to invariant natural killer T‐cells (iNKT). We have examined the role of the N‐linked glycans on the human CD1d (hCD1d) in modulating the responses of iNKT cells using a combination of cell‐free, cell‐based assays and in silico analyses ...
Bandyopadhyay S, Pradhan S.
europepmc +2 more sources
Neuraminidase construction and function [PDF]
Neuraminidase has been of interest for many years as a potential candidate for a universal influenza vaccine. This is due to the limited mutation on the head domain of the protein, specifically the active site where the enzyme lies.
Tucker, Joseph
core +1 more source
Structural and functional relationship between the receptor recognition and neuraminidase activities of the Newcastle disease virus hemagglutinin-neuraminidase protein: Receptor recognition is dependent on neuraminidase activity [PDF]
The terminal globular domain of the paramyxovirus hemagglutinin-neuraminidase (HN) glycoprotein spike has a number of conserved residues that are predicted to form its neuraminidase (NA) active site, by analogy to the influenza virus neuraminidase ...
Paul J. Mahon +13 more
core +1 more source
Effectiveness of neuraminidase inhibitors for preventing staff absenteeism during pandemic influenza. [PDF]
We used a deterministic SEIR (susceptible-exposed-infectious-removed) meta-population model, together with scenario, sensitivity, and simulation analyses, to determine stockpiling strategies for neuraminidase inhibitors that would minimize absenteeism ...
Vernon J. Lee +5 more
core +1 more source
The neuraminidase of Vibrio cholerae [PDF]
Over the past 25 years research on the pathogenesis of cholera has focused on the role of enterotoxin, largely to the neglect of the other extracellular components such as neuraminidase, mucinase and proteinase. The main object of this thesis has been to
Ollar, Robert A
core +7 more sources
Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK [PDF]
The sequence variation in a 934 base-pair region of the gene encoding the haemagglutinin-neuraminidase of five human parainfluenza virus type 3 (HPIV3) isolates was determined together with that of a prototype UK strain. All of the clinical isolates were
Easton, A. J. (Andrew J.) +1 more
core +1 more source
Influenza, as one of the most serious communicable respiratory infectious diseases, is caused by influenza viruses. Neuraminidase (NA), also referred to as sialidase, is an important protein on the influenza virus surface.
Sheng Zeng (235606) +7 more
core +1 more source
Economics of neuraminidase inhibitor stock piling for pandemic influenza, Singapore. [PDF]
We compared strategies for stock piling neuraminidase inhibitors to treat and prevent influenza in Singapore. Cost-benefit and cost-effectiveness analyses, with Monte Carlo simulations, were used to determine economic outcomes. A pandemic in a population
Stefan Ma +13 more
core +1 more source
Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Temperton, Nigel J. +12 more
core +1 more source
Homology modelling and insilico analysis of neuraminidase protein in H1N1 Influenza A virus
In this work, modelling of Neuraminidase protein of Influenza A virus (A/Himeji/1/2009(H1N1)) neuraminidase (NA) protein was done using Modeller 9V2.
Abhilash Manohar
doaj +1 more source

