Results 61 to 70 of about 43,769 (228)
Вопросы вирусологии, 2020 Introduction. The classic hemagglutination inhibition reaction (RTGA) is used to determine the level of antiviral antibodies in human and animal serum specimens.
Artem Yu. Fedorov, Oleg P. Zhirnov
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Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Babesiosis is a tick‐borne disease that poses a significant threat to animal health worldwide. In addition, climate change and the risk of human‐to‐human transmission through blood transfusion have made babesiosis an emerging disease in humans.
Assia Mouhand +4 more
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Polysialosides Outperform Sulfated Analogs for Binding with SARS‐CoV‐2
Small, EarlyView.Both sulfated and sialylated glycans present on the cell surface act as co‐receptors for the SARS‐CoV‐2 attachment. Polysialylated and sulfated dendritic polyglycerols are studied for their binding with SARS‐CoV‐2. In solution, dendritic polyglycerol sialosides (dPGSAs) bind significantly stronger (low nm) to SARS‐CoV‐2 than their sulfated analogs ...
Vinod Khatri +16 more
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A neuraminidase potency assay for quantitative assessment of neuraminidase in influenza vaccines [PDF]
npj Vaccines, 2019 AbstractNeuraminidase (NA) immunity leads to decreased viral shedding and reduced severity of influenza disease; however, NA content in influenza vaccines is currently not regulated, resulting in inconsistent quality and quantity of NA that can vary from manufacturer to manufacturer, from year to year, and from lot to lot.
Rose T. Byrne-Nash +5 more
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Neural Regeneration Research, 2015 With advances in biomedical methods, tissue-engineered materials have developed rapidly as an alternative to nerve autografts for the repair of peripheral nerve injuries. However, the materials selected for use in the repair of peripheral nerve injuries,
Yuan Gao +6 more
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Microneedle delivery systems for vaccines and immunotherapy
Smart Molecules, EarlyView.This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia +5 more
wiley +1 more source
mBio, 2019 The effectiveness of influenza vaccines against circulating A(H1N1)pdm09 viruses was modest for several seasons despite the absence of antigenic drift of hemagglutinin (HA), the primary vaccine component. Since antibodies against HA and neuraminidase (NA)
Jin Gao +13 more
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Small Methods, EarlyView.This work demonstrates the use of polymer‐tethered glycosylated gold nanoparticles for the label‐free evaluation of influenza virus binding in a simple microplate. Sialylated linear and branched glycans are integrated using a modular capture and assembly process. The microplate‐based assays are shown to correlate with biolayer interferometry and can be
Sarah‐Jane Richards +11 more
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Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada
Emerging Infectious Diseases, 2019 We identified an influenza B isolate harboring a Gly407Ser neuraminidase substitution in an immunocompromised patient in Canada before antiviral therapy.
Yacine Abed +6 more
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Network medicine and systems pharmacology approaches to predicting adverse drug effects
British Journal of Pharmacology, EarlyView.Identifying and understanding the relationships between drug intake and adverse effects that can occur due to inadvertent molecular interactions between drugs and targets is a difficult task, especially considering the numerous variables that can influence the onset of such events.
Alessio Funari +2 more
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