Results 81 to 90 of about 45,170 (239)

Effect of neuraminidase inhibitor (oseltamivir) treatment on outcome of hospitalised influenza patients, surveillance data from 11 EU countries, 2010 to 2020 [PDF]

open access: diamond, 2023
Cornelia Adlhoch   +19 more
openalex   +1 more source

Monitoring and Characterization of Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus, Japan, 2009–2010

open access: yesEmerging Infectious Diseases, 2011
To monitor and characterize oseltamivir-resistant (OR) pandemic (H1N1) 2009 virus with the H275Y mutation, we analyzed 4,307 clinical specimens from Japan by neuraminidase (NA) sequencing or inhibition assay; 61 OR pandemic (H1N1) 2009 viruses were ...
Makoto Ujike   +15 more
doaj   +1 more source

Inhibition of sialidase activity as a therapeutic approach

open access: yesDrug Design, Development and Therapy, 2018
Victor Yu Glanz,1 Veronika A Myasoedova,2 Andrey V Grechko,3 Alexander N Orekhov2,4 1Department of Genetics, Cytology and Bioengineering, Faculty of Biology and Medicine, Voronezh State University, Voronezh, Russia; 2Laboratory of Angiopathology ...
Glanz VY   +3 more
doaj  

Structural studies of type-B neuraminidase [PDF]

open access: bronze, 1993
Cassandra L White   +4 more
openalex   +1 more source

Influenza a Neuraminidase-Based Bivalent mRNA Vaccine Induces Th1-Type Immune Response and Provides Protective Effects in Mice

open access: yesVaccines
Vaccines are one of the most effective means of preventing influenza A, typically containing the hemagglutinin (HA) of the influenza A virus. However, antigenic drift and shift of the influenza A virus can lead to instability in vaccine efficacy ...
Mingyang Li   +10 more
doaj   +1 more source

The Development of a Novel Broad-Spectrum Influenza Polypeptide Vaccine Based on Multi-Epitope Tandem Sequences

open access: yesVaccines
Background: Polypeptide vaccines have the potential to improve immune responses by targeting conserved and weakly immunogenic regions in antigens. This study aimed to identify and evaluate the efficacy of a novel influenza universal vaccine candidate ...
Song Zhao   +7 more
doaj   +1 more source

Structure−Activity Relationship Studies of Novel Carbocyclic Influenza Neuraminidase Inhibitors

open access: green, 1998
Choung U. Kim   +9 more
openalex   +1 more source

Substitution of I222L-E119V in neuraminidase from highly pathogenic avian influenza H7N9 virus exhibited synergistic resistance effect to oseltamivir in mice [PDF]

open access: gold, 2021
Jing Tang   +10 more
openalex   +1 more source

Increasing Oral Absorption of Polar Neuraminidase Inhibitors: A Prodrug Transporter Approach Applied to Oseltamivir Analogue

open access: green, 2012
Deepak Gupta   +6 more
openalex   +2 more sources

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