Results 1 to 10 of about 134,518 (195)
Physical Cues of Matrices Reeducate Nerve Cells
Frontiers in Cell and Developmental Biology, 2021 The behavior of nerve cells plays a crucial role in nerve regeneration. The mechanical, topographical, and electrical microenvironment surrounding nerve cells can activate cellular signaling pathways of mechanical transduction to affect the behavior of ...
Yiqian Luo +5 more
doaj +1 more source
环境与职业医学, 2022 BackgroundAluminum (Al) can cause irreversible damage to neurons and synapses function, and the mechanism may be connected to mitochondrial damage caused by glycogen synthase kinase-3β (GSK-3β) regulating dynamin-related protein 1 (DRP1), resulting in ...
Meng LI +5 more
doaj +1 more source
环境与职业医学, 2021 BackgroundAluminum can induce irreversible structural and synaptic functional damage, and the associated mechanism may be related to the neurite damage regulated by glycogen synthase kinase-3β (GSK-3β)/collapsin response mediator protein 2 (CRMP2 ...
Huifang ZHANG +4 more
doaj +1 more source
Revista de Ciências da Saúde Nova Esperança, 2021 A hanseníase é uma doença infecciosa, granulomatosa, de caráter crônico, causada pelo Mycobacterium leprae, que tem predileção pela pele e nervos periféricos. Alguns pacientes apresentam episódios inflamatórios, conhecidos como estado reacional ou reação
Maite de Souza e Silva +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Microglia, the primary immune cells of the brain, significantly influence the fate of neurons after neural damage. Depending on the local environment, they exhibit a wide range of phenotypes, including patrolling (naïve), proinflammatory, and anti ...
Julianna Lilienberg +5 more
doaj +1 more source
Biology, 2021 B-cell lymphoma-extra large (Bcl-xL) is a mitochondrial protein known to inhibit mitochondria-dependent intrinsic apoptotic pathways. An increasing number of studies have demonstrated that Bcl-xL is critical in regulating neuronal energy metabolism and ...
Joseph Jansen +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Studies on neural development and neuronal regeneration after injury are mainly based on animal models. The establishment of pluripotent stem cell (PSC) technology, however, opened new perspectives for better understanding these processes in human models
Julianna Lilienberg +9 more
doaj +1 more source
RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth
Biomolecules, 2021 Diacylglycerol kinase β (DGKβ) is an enzyme that converts diacylglycerol to phosphatidic acid and is mainly expressed in the cerebral cortex, hippocampus and striatum.
Takuya Kano +7 more
doaj +1 more source
BIO-PROTOCOL, 2016 Neurite outgrowth in culture provides an easy way to determine the effects of a particular substrate or exogenous factor on neuron behavior. Dissociated neurons can be plated on a variety of substrates and the length of the longest neurite outgrowth can be compared.
Angela Filous, Jerry Silver
openaire +3 more sources
Adhesion and patterning of cortical neurons on polyethylenimine and fluorcarboncoated surfaces [PDF]
, 2000 In this study adhesion and patterning of cortical neurons on modified glass surfaces was investigated. Patterns of cortical neurons were prepared with a combination of polyethylenimine (PEI) and plasma-deposited fluorocarbon (FC).
Goedbloed, M.H. +2 more
core +11 more sources