Neuroactive steroids, their metabolites, and neuroinflammation [PDF]
Journal of Molecular Endocrinology, 2012 Neuroinflammation represents a common feature of many neurodegenerative diseases implicated both in their onset and progression. Neuroactive steroids act as physiological regulators and protective agents in the nervous system. Therefore, the attention of biomedical research has been recently addressed in evaluating whether neuroactive steroids, such as
S. Giatti +3 more
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Role of neuroactive steroids in the peripheral nervous system [PDF]
Frontiers in Endocrinology, 2011 Several reviews have so far pointed out on the relevant physiological and pharmacological role exerted by neuroactive steroids in the central nervous system.
Roberto Cosimo eMelcangi +6 more
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Ambulatory Neuroproprioceptive Facilitation and Inhibition Physical Therapy Improves Clinical Outcomes in Multiple Sclerosis and Modulates Serum Level of Neuroactive Steroids: A Two-Arm Parallel-Group Exploratory Trial [PDF]
Life, 2020 Background: Only few studies have monitored the potential of physical activity training and physical therapy to modulate the reaction of the endocrine system.
Gabriela Angelova +11 more
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Neuroactive Steroids and Cognitive Functions in First-Episode Psychosis Patients and Their Healthy Siblings [PDF]
Frontiers in Psychiatry, 2019 Background: Neuroactive steroids (NAS) affect neurotransmitter systems and cognition; thus, they play role in etiopathogenesis of psychiatric disorders.Aims: The primary aim was to examine cognition and effects of NAS on cognitive functioning in first ...
Pavel Knytl +18 more
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Levels of neuroactive steroids are elevated in those who develop first-onset depression early in pregnancy [PDF]
Frontiers in PsychiatryBackgroundAllopregnanolone (ALLO) plays a key role in the pathogenesis of postpartum depression. However, ALLO levels have been variably associated with depression during pregnancy.
Elizabeth S. Wenzel +12 more
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Stress, ethanol, and neuroactive steroids [PDF]
Pharmacology & Therapeutics, 2007 Neurosteroids play a crucial role in stress, alcohol dependence and withdrawal, and other physiological and pharmacological actions by potentiating or inhibiting neurotransmitter action. This review article focuses on data showing that the interaction among stress, ethanol, and neuroactive steroids may result in plastic molecular and functional changes
Biggio G +4 more
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Neuroactive Steroids Reverse Tonic Inhibitory Deficits in Fragile X Syndrome Mouse Model [PDF]
Frontiers in Molecular Neuroscience, 2019 Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. A reduction in neuronal inhibition mediated by γ-aminobutyric acid type A receptors (GABAARs) has been implicated in the pathophysiology of FXS.
Amit Modgil +6 more
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Plasma concentrations of steroid precursors, steroids, neuroactive steroids, and neurosteroids in healthy neonatal foals from birth to 7 days of age [PDF]
Journal of Veterinary Internal Medicine, 2019 Background Transient hypothalamic‐pituitary‐adrenal axis dysfunction occurs in critically ill foals with sepsis and neonatal maladjustment syndrome (NMS). Cortisol is the most commonly measured steroid.
Monica Aleman +3 more
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Physiopathological Role of Neuroactive Steroids in the Peripheral Nervous System. [PDF]
Int J Mol Sci, 2020 Peripheral neuropathy (PN) refers to many conditions involving damage to the peripheral nervous system (PNS). Usually, PN causes weakness, numbness and pain and is the result of traumatic injuries, infections, metabolic problems, inherited causes, or ...
Falvo E +3 more
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Peripartum depression: Current considerations on classification, biological importance and therapeutic potential of neuroactive steroids [PDF]
Vojnosanitetski Pregled, 2022 nema
Marković Miloš, Milovanović Srđan
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