Results 21 to 30 of about 4,357 (193)

Neuroactive Steroids and Perinatal Depression: a Review of Recent Literature [PDF]

Current Psychiatry Reports, 2018
Jennifer L Payne, Lauren M Osborne, Payne Jennifer L   +2 more
exaly   +2 more sources

Neuroactive Steroids in Schizophrenia [PDF]

The Canadian Journal of Psychiatry, 2005
Schizophrenia is a psychiatric disorder with a complicated pathophysiology, involving many biochemical abnormalities in the brain. Because neuroactive steroids (NASs) modulate neurotransmitter systems that are implicated in the pathology of schizophrenia, recent research has focused on examining the role that NASs play in the illness. Although research
Yanina, Shulman, Philip G, Tibbo
openaire   +2 more sources

Advances in pharmacotherapy for postpartum depression: a structured review of standard-of-care antidepressants and novel neuroactive steroid antidepressants

Therapeutic Advances in Psychopharmacology, 2022
Postpartum depression is one of the most common morbidities of childbearing, yet it is underdiagnosed and undertreated with negative consequences for mother and offspring.
Yardana Kaufman, Sara V. Carlini, Kristina M. Deligiannidis   +2 more
doaj   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Eser, Daniela, Eser D., Baghai, Thomas C., Schule C., Romeo, Elena, Baghai T. C., Schuele, Cornelius, Rupprecht R., Rupprecht, Rainer, Eser D., Schule C., Baghai T.C., Romeo E., Rupprecht R.   +9 more
core   +1 more source

Widespread Cortical Thickness Is Associated With Neuroactive Steroid Levels

Frontiers in Neuroscience, 2019
BackgroundNeuroactive steroids are endogenous molecules with regenerative and neuroprotective actions. Both cortical thickness and many neuroactive steroid levels decline with age and are decreased in several neuropsychiatric disorders.
Rajendra A. Morey, Rajendra A. Morey, Rajendra A. Morey, Sarah L. Davis, Sarah L. Davis, Courtney C. Haswell, Courtney C. Haswell, Jennifer C. Naylor, Jennifer C. Naylor, Jason D. Kilts, Jason D. Kilts, Steven T. Szabo, Steven T. Szabo, Larry J. Shampine, Larry J. Shampine, Gillian J. Parke, Gillian J. Parke, Delin Sun, Delin Sun, Chelsea A. Swanson, Chelsea A. Swanson, Henry R. Wagner, Henry R. Wagner, Henry R. Wagner, Mid-Atlantic MIRECC Workgroup, Christine E. Marx, Christine E. Marx   +26 more
doaj   +1 more source

Organizational Effects of Estrogens and Androgens on Estrogen and Androgen Receptor Expression in Pituitary and Adrenal Glands in Adult Male and Female Rats

Frontiers in Neuroanatomy, 2022
Sex steroid hormones, such as androgens and estrogens, are known to exert organizational action at perinatal periods and activational effects during adulthood on the brain and peripheral tissues.
Natalia Lagunas, José Manuel Fernández-García, José Manuel Fernández-García, Noemí Blanco, Antonio Ballesta, Antonio Ballesta, Beatriz Carrillo, Beatriz Carrillo, Maria-Angeles Arevalo, Maria-Angeles Arevalo, Paloma Collado, Paloma Collado, Helena Pinos, Helena Pinos, Daniela Grassi, Daniela Grassi, Daniela Grassi, Daniela Grassi   +17 more
doaj   +1 more source

Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features

Biology of Sex Differences, 2018
Background Disruption of axonal transport plays a pivotal role in diabetic neuropathy. A sex-dimorphism exists in the incidence and symptomatology of diabetic neuropathy; however, no studies so far have addressed sex differences in axonal motor proteins ...
Marzia Pesaresi, Silvia Giatti, Roberto Spezzano, Simone Romano, Silvia Diviccaro, Tiziana Borsello, Nico Mitro, Donatella Caruso, Luis Miguel Garcia-Segura, Roberto Cosimo Melcangi   +9 more
doaj   +1 more source

Plasticity of GABAA Receptors during Pregnancy and Postpartum Period: From Gene to Function

Neural Plasticity, 2015
Pregnancy needs complex pathways that together play a role in proper growth and protection of the fetus preventing its premature loss. Changes during pregnancy and postpartum period include the manifold machinery of neuroactive steroids that plays a ...
Valentina Licheri, Giuseppe Talani, Ashish A. Gorule, Maria Cristina Mostallino, Giovanni Biggio, Enrico Sanna   +5 more
doaj   +1 more source

Neuroactive Steroid–Gut Microbiota Interaction in T2DM Diabetic Encephalopathy

Biomolecules, 2023
The pathological consequences of type 2 diabetes mellitus (T2DM) also involve the central nervous system; indeed, T2DM patients suffer from learning and memory disabilities with a higher risk of developing dementia.
Silvia Diviccaro, Lucia Cioffi, Rocco Piazza, Donatella Caruso, Roberto Cosimo Melcangi, Silvia Giatti   +5 more
doaj   +1 more source

Neuroactive Steroids in First-Episode Psychosis: A Role for Progesterone? [PDF]

Schizophr Res Treatment, 2016
Neuroactive steroids may play a role in the pathophysiology of psychotic disorders, but few studies examined this issue. We compared serumlevels of cortisol, testosterone, dehydroepiandrosterone, and progesterone between a representative sample of ...
Belvederi Murri M, Fanelli F, Pagotto U, Bonora E, Triolo F, Chiri L, Allegri F, Mezzullo M, Menchetti M, Mondelli V, Pariante C, Berardi D, Tarricone I.   +12 more
europepmc   +3 more sources