Results 61 to 70 of about 268,028 (214)

Intermittent hypoxia effect on osteoclastogenesis stimulated by neuroblastoma cells. [PDF]

PLoS ONE, 2014
Neuroblastoma is the most common extracranial pediatric solid tumor. Intermittent hypoxia, which is characterized by cyclic periods of hypoxia and reoxygenation, has been shown to positively modulate tumor development and thereby induce tumor growth ...
Vasantha Kumar Bhaskara, Indra Mohanam, Meena Gujrati, Sanjeeva Mohanam   +3 more
doaj   +1 more source

Electrolyte-gated organic synapse transistor interfaced with neurons [PDF]

Organic Electronics, 38, 21-28 (2016), 2016
We demonstrate an electrolyte-gated hybrid nanoparticle/organic synapstor (synapse-transistor, termed EGOS) that exhibits short-term plasticity as biological synapses. The response of EGOS makes it suitable to be interfaced with neurons: short-term plasticity is observed at spike voltage as low as 50 mV (in a par with the amplitude of action potential ...
arxiv   +1 more source

Recent advances in neuroblastoma.

New England Journal of Medicine, 2010
Neuroblastoma, an embryonal cancer of the autonomic nervous system, is the most common cancer diagnosed during the first year of life. Although neuroblastoma accounts for disproportionately high morbidity and mortality among childhood cancers, it has one
J. Maris
semanticscholar   +1 more source

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

Nature Communications, 2020
Neuroblastoma is a pediatric malignancy with heterogeneous clinical outcomes. To better understand neuroblastoma pathogenesis, here we analyze whole-genome, whole-exome and/or transcriptome data from 702 neuroblastoma samples.
Samuel W. Brady, Yanling Liu, Xiaotu Ma, A. Gout, Kohei Hagiwara, Xin Zhou, Jian Wang, Michael Macias, Xiaolong Chen, J. Easton, H. Mulder, Michael C. Rusch, Lu Wang, J. Nakitandwe, Shaohua Lei, Eric M Davis, A. Naranjo, Cheng Cheng, J. Maris, J. Downing, N. Cheung, M. Hogarty, M. Dyer, Jinghui Zhang   +23 more
semanticscholar   +1 more source

Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Note: In this manuscript as well as in the original published version of this article the word "Polyphenon" was incorrectly spelled in the title as ...
Adrian J. Thrasher, Arturo Sala, Chow, Croce, Dale, Daniel A. Morgenstern, Giorgia Santilli, Ikeda, Izabela Piotrowska, John Anderson, Katie Pearson, Marco D'Alicarnasso, Nourredine Himoudi, Olesya Chayka, Sandra Cantilena   +14 more
core   +2 more sources

Sunitinib suppress neuroblastoma growth through degradation of MYCN and inhibition of angiogenesis.

PLoS ONE, 2014
Neuroblastoma, a tumor of the peripheral sympathetic nervous system, is the most common and deadly extracranial tumor of childhood. The majority of high-risk neuroblastoma exhibit amplification of the MYCN proto-oncogene and increased neoangiogenesis ...
Raul Calero, Esther Morchon, John Inge Johnsen, Rosario Serrano   +3 more
doaj   +1 more source

Bioinformatics analysis of miRNAs in the neuroblastoma 11q-deleted region reveals a role of miR-548l in both 11q-deleted and MYCN amplified tumour cells

Scientific Reports, 2022
Neuroblastoma is a childhood tumour that is responsible for approximately 15% of all childhood cancer deaths. Neuroblastoma tumours with amplification of the oncogene MYCN are aggressive, however, another aggressive subgroup without MYCN amplification ...
Sanja Jurcevic, Simon Keane, Emmy Borgmästars, Zelmina Lubovac-Pilav, Katarina Ejeskär   +4 more
doaj   +1 more source

Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Childrens Oncology Group. [PDF]

, 2012
Purpose. (123)I-metaiodobenzylguanidine (MIBG) is used for the diagnostic evaluation of neuroblastoma. We evaluated the relationship between norepinephrine transporter (NET) expression and clinical MIBG uptake. Methods. Quantitative reverse transcription
Attiyeh, Edward, Baker, David, Batra, Vandana, Dubois, Steven, Geier, Ethan, Giacomini, Kathleen, Hogarty, Michael, Kreissman, Susan, London, Wendy, Maris, John, Martinez, Daniel, Matthay, Katherine, Naranjo, Arlene, Neuhaus, John, Pawel, Bruce, Segal, Mark, Yanik, Greg, Yee, Sook   +17 more
core   +2 more sources

Neuroblastoma—A Neural Crest Derived Embryonal Malignancy

Frontiers in Molecular Neuroscience, 2019
Neuroblastoma is a neural crest derived malignancy of the peripheral nervous system and is the most common and deadliest tumor of infancy. It is characterized by clinical heterogeneity with a disease spectrum ranging from spontaneous regression without ...
J. Johnsen, Cecilia Dyberg, M. Wickström   +2 more
semanticscholar   +1 more source

Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas [PDF]

, 2011
Copyright © 2011 Cantilena et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and ...
Cantilena, S, Chayka, O, Pastorino, F, Pezzolo, A, Pistoia, V, Ponzoni, M, Sala, A   +6 more
core   +2 more sources