Results 251 to 260 of about 5,310,608 (313)

Editorial: Advancing neurodegenerative disease biomarkers: the role of neuroimaging in TDP-43 and tau proteinopathies. [PDF]

Front Neurosci
Gatto RG, Youssef H, Gao Y.
europepmc   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Investigating Disordered Eating Behaviours Among Individuals Living With Neurodegenerative Disease: A Scoping Review. [PDF]

J Hum Nutr Diet
Buttifant E, Allogmanny S, Probst Y.
europepmc   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

Evaluating the Role of AI Assistants in Accelerating Neurodegenerative Disease Research: Opportunities and Translational Limitations. [PDF]

Neuropsychiatr Dis Treat
Yu X, Yao Q.
europepmc   +1 more source

Correspondence on: "Neurolymphatic clearance in neurodegenerative disease: Emerging mechanisms and potential translational strategies". [PDF]

JPRAS Open
Al Sammour C, De Lissnyder N, Marron Mendes V, Schettino M.   +3 more
europepmc   +1 more source

Vascular burden attenuates the TDP-43-TMEM106B pathological relationship in neurodegenerative disease with and without Alzheimer disease neuropathological change. [PDF]

J Neuropathol Exp Neurol
Dopler MB, Corbett C, Gonzalez AD, Ghaseminejad-Bandpey A, Keating M, Clarke KM, Ogunbona OB, Maestre G, Seshadri S, Etemadmoghadam S, Flanagan ME.   +10 more
europepmc   +1 more source

Brain-First vs. Body-First Models in Neurodegenerative Disease: A Perspective Review. [PDF]

NeuroSci
Forte G, Casagrande M.
europepmc   +1 more source

Response to correspondence on: "Neurolymphatic clearance in neurodegenerative disease: Emerging mechanisms and potential translational strategies". [PDF]

JPRAS Open
Fabi A, Guzman R, Busche MA, Kappos EA.
europepmc   +1 more source

Beyond prion-like spreading in neurodegenerative disease. [PDF]

Alzheimers Dement
Meisl G, Rowe JB, Klenerman D.
europepmc   +1 more source