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Anosognosia in neurodegenerative disease
Neurocase, 2011Patients with neurological disorders are often partially or completely unaware of the deficits caused by their disease. This impairment is referred to as anosognosia, and it is very common in neurodegenerative disease, particularly in frontotemporal dementia.
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Prions and neurodegenerative diseases
Current Opinion in Genetics & Development, 2000The long-term, progressive decay of the central nervous system typifies prion diseases, a group of rare, transmissible maladies affecting humans, sheep, cattle and some other types of mammal. Little is known about the early molecular events in its pathogenesis but the diverse roles of PrP, the prion protein, in its destructive action have recently been
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Sleep and Neurodegenerative Diseases
Seminars in Neurology, 2009Sleep disturbances are common in neurodegenerative diseases. Disturbed sleep can result in fatigue, irritability, morning headaches, impaired motor and cognitive skills, depression, and daytime somnolence. The major sleep complaints include insomnia, hypersomnia, parasomnia, excessive nocturnal motor activity, circadian sleep-wake rhythm disturbance ...
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Biomarkers in Neurodegenerative Diseases
2017The past decade has seen tremendous efforts in biomarker discovery and validation for neurodegenerative diseases. The source and type of biomarkers has continued to grow for central nervous system diseases, from biofluid-based biomarkers (blood or cerebrospinal fluid (CSF)), to nucleic acids, tissue, and imaging.
Andreas, Jeromin, Robert, Bowser
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Epigenetics in Neurodegenerative Diseases
Healthy brain functioning requires a continuous fine-tuning of gene expression, involving changes in the epigenetic landscape and 3D chromatin organization. Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD) are three multifactorial neurodegenerative diseases (NDDs) that are partially explained by genetics (Brigitte, van Zundert, Martin, Montecino
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Receptors in neurodegenerative diseases
Pharmaceutica Acta Helvetiae, 2000The ability of trophic factors to regulate developmental neuronal survival and adult nervous system plasticity suggests the use of these molecules to treat neurodegeneration associated with human diseases, such as Alzheimer's, Huntington's and Parkinson's disease, of amyotrophic lateral sclerosis and peripheral sensory neuropathies.
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SYK coordinates neuroprotective microglial responses in neurodegenerative disease
Cell, 2022Hannah Ennerfelt +2 more
exaly
Residential greenness, air pollution and incident neurodegenerative disease: A cohort study in China
Science of the Total Environment, 2023Zhanghang Zhu, Luhua Yu, Lisha Xu
exaly
Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated
Brain, 2023John L Robinson +2 more
exaly

