Results 81 to 90 of about 278,007 (254)

Neuroendocrine markers are expressed in human mammary glands

, 2010
BackgroundRegulatory peptides have previously been detected in epithelial cells of human mammary glands. As these peptides are produced by scattered neuroendocrine cells in the epithelium of other tissues the aim of this study was to investigate whether ...
Janson, Eva Tiensuu,, Saras, Jan,, Saras, J, Stridsberg, Mats,, Amini, Rose-Marie,, Grönberg, Malin,, Grönberg, M, Amini, R-M, Janson, ET, Stridsberg, M   +9 more
core   +1 more source

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin, Zhimin Lv, Chao Bian, Qibin Yang, Na Zhou, Jianguang Qin, Shengming Sun   +6 more
wiley   +1 more source

68Ga-DOTA-TATE PET/CT improves accuracy and guides management in multiple endocrine neoplasia type 1 (MEN-1) patients with suspected duodeno-pancreatic neuroendocrine tumours

Endocrine Oncology
Purpose: To evaluate the added benefit and accuracy of 68Ga-DOTA-TATE PET/CT scans in detecting duodeno-pancreatic neuroendocrine tumours (dpNETs) compared to conventional cross-sectional imaging with CT or MRI scans in patients with multiple endocrine ...
Kalyan Vamshi Vemulapalli, Kalyan Mansukhbhai Shekhda, Gowri Ratnayake, Gopinath Gnanasegaran, Ann-Marie Quigley, Aimee R Hayes, Bernard Khoo, Dalvinder Mandair, Christos Toumpanakis, Martyn Caplin, Ashley B Grossman, Shaunak Navalkissoor   +11 more
doaj   +1 more source

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source

The effect of long-term exposure to moderately high ambient temperature on rat pituitary corticotropes: immunohistomorphometric and hormonal study

, 2018
18th Congress of the European NeuroEndocrine Association; 2018 Oct 17-20; Wrocław, Poland. European NeuroEndocrine Association; 2018.
Pendovski, Lazo, Ušćebrka, Gordana, Potrebić Stefanović, Milica, Milošević, Verica, Ajdžanović, Vladimir, Sretenović, Jasmina, Popovska-Perčinić, Florina, Jarić, Ivana   +7 more
core   +5 more sources

Molecular pathology of pancreatic neuroendocrine neoplasms

, 2015
Pancreatic neuroendocrine neoplasms (PanNENs) are a heterogeneous group of lesions exhibiting different genetic and epigenetic characteristics that affect the biological behavior of the tumor.
Daniela Furlan, FURLAN, DANIELA
core   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

The neuroendocrine immune network in ageing /

, 2004
The book describes the mechanisms involved in the maintenance of neuroendocrine-immune interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability.
Mocchegiani, Eugenio., Straub, Rainer H.
core  

Biochemical Testing in Patients with Neuroendocrine Tumors

, 2015
Neuroendocrine tumors are usually slow-growing tumors. Many of these are capable of secreting peptide hormones or biogenic amines that may lead to endocrine syndromes.
Granberg, Dan,, Granberg, D,, Dan Granberg   +2 more
core   +1 more source