Results 41 to 50 of about 87,175,870 (148)

Prevalence of Oral Alterations and Correlation Between Oral and Cutaneous Neurofibromas in Neurofibromatosis Type 1: A Retrospective Case–Control Study

Journal of Oral Pathology &Medicine, Volume 55, Issue 1, Page 155-160, January 2026.
ABSTRACT Objective The aim of this study was to determine the prevalence of oral alterations detectable through physical examination in NF1 individuals. Additionally, we assessed the correlation between the number of oral and cutaneous neurofibromas. Design This retrospective study evaluated oral alterations in individuals with and without NF1.
Pâmella de Pinho Montovani, Gabriela Pizão Werneck Moreira da Costa, Rafaela Elvira Rozza‐de‐Menezes, Karin Soares Cunha   +3 more
wiley   +1 more source

La Neurofibromatose de type 1

, 2021
La neurofibromatose de type 1 (NF1) est une maladie génétique dont le phénotype est très variable. Elle est caractérisée par de nombreuses manifestations cliniques dont les principales sont cutanées, ophtalmologiques et neurologiques.
Nicolas, Lise, Vadot, Laura
core  

Tumor maligno da bainha dos nervos periféricos do pulmão: A propósito de um caso clínico

Revista Portuguesa de Pneumologia, 2010
Resumo: Os tumores malignos da bainha dos nervos periféricos correspondem a um grupo raro de sarcomas de tecidos moles que tendem a ocorrer em doentes com neurofibromatose tipo 1 ou vários anos após tratamentos de radioterapia.
N. Serrano Marçal, E. Teixeira, R. Sotto-Mayor, A. Manique, P. Campos, J. Cruz, M. Mendes de Almeida, A. Bugalho de Almeida   +7 more
doaj   +1 more source

Nanodroplet‐Array‐Plattform zur integrierten Synthese und Screening von MEK Inhibitoren: Ein miniaturisierter Ansatz für die frühe Pharmaforschung

Angewandte Chemie, Volume 137, Issue 48, November 24, 2025.
Wir präsentieren eine Nanodroplet‐Array‐Plattform, die die Integration von Festphasensynthese, MALDI‐MS‐Analyse und zellbasiertem Screening von 325 potenziellen MEK‐Inhibitoren (Mitogen‐aktivierte‐Proteinkinase‐Kinase) in Nanoliter‐Volumina ermöglicht.
Maximilian Seifermann, Julius Höpfner, Liana Bauer, Divya Varadharajan, Stefan Schmidt, Björn Fröhlich, Benjamin Wellenhofer, Charlotte Luchena, Carsten Hopf, Anna A. Popova, Pavel A. Levkin   +10 more
wiley   +1 more source

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

Developmental Medicine &Child Neurology, Volume 67, Issue 8, Page 1004-1025, August 2025.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes, Velda X. Han, Shrujna Patel, Michelle A. Farrar, Deepak Gill, Shekeeb S. Mohammad, Russell C. Dale   +6 more
wiley   +1 more source

Diagnostic Importance of Cutaneous Manifestations of Neurofibromatosis—A Systematic Review

Neurology and Clinical Neuroscience, Volume 13, Issue 3, Page 165-173, May 2025.
ABSTRACT A class of hereditary diseases known as neurofibromatoses results in tumor growth on tissue from nerves. The spinal cord, nerves, and brain are among the parts of the nervous framework where these tumors can form. Similar to other genetic disorders, neurofibromatosis discloses complicated phenotypes, exhibiting varying benign and malignant ...
Hina Aslam, Inshal Jawed, Ali Farhan, Vikash Karmani, Agha Muhammad Wali Mirza, Farah Alam, Hina Khan, Abdul Haseeb, Mohammad Omer Alam, Javed Iqbal, Brijesh Sathian, Abu Huraira Bin Gulzar   +11 more
wiley   +1 more source

La neurofibromatose de type I

The Pan African Medical Journal, 2014
La neurofibromatose de type 1 (NF1) ou maladie de Recklinghausen est une génodermatose autosomique dominante, elle touche de 1/3000 à 1/4000 personnes. La NF1 est caractérisée par une variabilité de son expression clinique qu'on peut retrouver au sein de
Kbira El Morabite, Baderddine Hassam
doaj   +1 more source

Lamotrigine for cognitive deficits associated with neurofibromatosis type 1: A phase II randomized placebo‐controlled trial

Developmental Medicine &Child Neurology, Volume 67, Issue 4, Page 537-549, April 2025.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16157 In this double‐blind, placebo‐controlled, randomized clinical trial, 31 adolescents with neurofibromatosis type 1 (NF1) were enrolled to test the effects of lamotrigine on cognitive functioning.
Myrthe J. Ottenhoff, Sabine E. Mous, Jesminne Castricum, André B. Rietman, Rianne Oostenbrink, Thijs van der Vaart, Joke H. M. Tulen, Alba Parra, Federico J. Ramos, Eric Legius, Henriette A. Moll, Ype Elgersma, Marie‐Claire Y. de Wit, ENCORE Expertise Center for NF1, Walter Taal, Sarah van Dijk, Laura de Graaff, Yvette van Ierland, Margreethe van Vliet, Jeroen Legerstee, Pieter de Nijs, Maarten van Schijndel   +21 more
wiley   +1 more source

An Unexplored Diversity for Adaptation of Germination to High Temperatures in Brassica Species

Evolutionary Applications, Volume 18, Issue 3, March 2025.
ABSTRACT Elevated temperatures inhibit the germination of a concerning number of crop species. One strategy to mitigate the impact of warming temperatures is to identify and introgress adaptive genes into elite germplasm. Diversity must be sought in wild populations, coupled with an understanding of the complex pattern of adaptation across a broad ...
M. Tiret, M.‐H. Wagner, L. Gay, E. Chenel, A. Dupont, C. Falentin, L. Maillet, F. Gavory, K. Labadie, S. Ducournau, A.‐M. Chèvre   +10 more
wiley   +1 more source

Aneurisma da artéria vertebral extracraniana em puérpera portadora de neurofibromatose clássica Extracranial vertebral artery aneurysm during the puerperium in women with neurofibromatosis type 1

Jornal Vascular Brasileiro, 2005
Paciente de 26 anos, no 10º dia de puerpério, apresentou dor súbita em região cervical esquerda irradiada para região supraclavicular do mesmo lado, seguida de aparecimento de massa pulsátil. Relatava hipertensão sistólica média de 160 mmHg, e diastólica
Carla Aparecida Faccio Bosnardo, Rodrigo Machado Landim, Ana Terezinha Guillaumon, Marcus Ageu Baptista, Ricardo Henklain   +4 more
doaj   +1 more source