Results 11 to 20 of about 129,345 (287)
Neurogenesis or non-neurogenesis: that is the question [PDF]
Journal of Clinical Investigation, 2014 Neural stem/precursor cells (NPCs) that reside within germinal niches of the adult CNS have more complex roles than previously expected. In addition to their well-documented neurogenic functions, emerging evidence indicates that NPCs exert non-neurogenic functions that contribute to the regulation and preservation of tissue homeostasis under both ...
MARTINO , GIANVITO +2 more
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Cells, 2022 One of the most intriguing dogmas in neurosciences—the empirical lack of brain neuronal regeneration in adulthood onwards to late life—began to be debunked initially by research groups focused on understanding postnatal (early days/weeks of murine and guinea pigs) neurodevelopmental and neuroplastic events [...]
Andreia Vaz, Inês Ribeiro, Luísa Pinto
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Metabolism and neurogenesis [PDF]
Current Opinion in Neurobiology, 2017 The generation of neurons in the developing and adult mammalian brain by neural stem/progenitor cells (NSPCs) depends on a tight control of NSPC activity and neuronal differentiation that is regulated by a plethora of intrinsic and extrinsic molecular cues.
Knobloch, Marlen, Jessberger, Sebastian
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Appetite for Neurogenesis [PDF]
Developmental Cell, 2017 Adult neural stem cells (NSCs) in the ventricular-subventricular zone (V-SVZ) produce diverse olfactory bulb (OB) neurons. In a recent paper in Science, Paul et al. (2017) show that hypothalamic propiomelanocortin (POMC) neurons innervate the anterior ventral V-SVZ and regulate deep granule interneuron production depending on feeding behavior.
Kristen L, Zuloaga, Sally, Temple
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Neurogenesis and Epilepsy [PDF]
Epilepsia, 2010 Abstract Medial temporal lobe epilepsy (mTLE) is a common and often intractable form of epilepsy. Approximately 50 million people suffer from different epilepsies worldwide,1 30%–40% of whom may continue to have poorly controlled seizures despite therapy.2,3 Medial TLE is estimated to be the most common cause of intractable epilepsy in ...
Parent, Jack M., Kron, Michelle M.
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eLife, 2016 Experiments on fruit flies are shedding new light on the evolution and development of the nervous system in metamorphosing insects.
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Development, 2014 A unique feature of humans is the complexity of our central nervous system. A fully functional brain requires that billions of neurons make specific contacts in a highly coordinated way, an issue that is still not well understood. The neural retina constitutes an excellent system with which to analyze key aspects of neurogenesis and circuit formation ...
Lázaro, Centanin, Joachim, Wittbrodt
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Scientific Reports, 2022 Opioids are the therapeutic agents of choice to manage moderate to severe pain in patients with advanced cancer, however the unpredictable inter-individual response to opioid therapy remains a challenge for clinicians.
Deniz Ozberk +10 more
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Frontiers in Cell and Developmental Biology, 2021 TBL1XR1 gene is associated with multiple developmental disorders presenting several neurological aspects. The relative protein is involved in the modulation of important cellular pathways and master regulators of transcriptional output, including nuclear
Giuseppina Mastrototaro +19 more
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Proton MR Spectroscopy of Neural Stem Cells: Does the Proton-NMR Peak at 1.28 ppm Function As a Biomarker for Cell Type or State? [PDF]
, 2011 Recently, a peak at 1.28 ppm in proton magnetic resonance spectroscopy (^1H-MRS) of neural stem cells (NSCs) was introduced as a noninterventional biomarker for neurogenesis in vivo. This would be an urgently needed requisite for translational studies in
Brandt, Moritz +9 more
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