Results 11 to 20 of about 218,517 (358)

Quantifying the behavioural relevance of hippocampal neurogenesis [PDF]

, 2014
Few studies that examine the neurogenesis--behaviour relationship formally establish covariation between neurogenesis and behaviour or rule out competing explanations. The behavioural relevance of neurogenesis might therefore be overestimated if other mechanisms account for some, or even all, of the experimental effects.
Fuss, Johannes, Gass, Peter, Lazic, Stanley E.   +2 more
arxiv   +9 more sources

Using causal models to distinguish between neurogenesis-dependent and -independent effects on behaviour [PDF]

, 2011
There has been a substantial amount of research on the relationship between hippocampal neurogenesis and behaviour over the past fifteen years, but the causal role that new neurons have on cognitive and affective behavioural tasks is still far from clear.
Stanley E. Lazic
arxiv   +5 more sources

Neurogenesis Deep Learning [PDF]

, 2016
Neural machine learning methods, such as deep neural networks (DNN), have achieved remarkable success in a number of complex data processing tasks. These methods have arguably had their strongest impact on tasks such as image and audio processing - data processing domains in which humans have long held clear advantages over conventional algorithms.
Aimone, James B., Carlson, Kristofor D., Cox, Jonathan A., Draelos, Timothy J., James, Conrad D., Lamb, Christopher C., Miner, Nadine E., Severa, William M., Vineyard, Craig M.   +8 more
arxiv   +3 more sources

Computational Models of Adult Neurogenesis [PDF]

, 2004
Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the context of and adult brain. Here we propose two models where new projection neurons are incorporated.
Altman, Alvarez-Buylla, Carleton, Cecchi, Durbin, Friedrich, Fritzke, Goldman, Guillermo A. Cecchi, Kempermann, Linsker, Marcelo O. Magnasco, Petreanu, Rochefort   +13 more
arxiv   +3 more sources

Network structure determines patterns of network reorganization during adult neurogenesis [PDF]

arXiv, 2009
New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered connectivity patterns.
Ben-Jacob, Eshel, Parent, Jack M., Sander, Leonard M., Schneider-Mizell, Casey M., Zochowski, Michal   +4 more
arxiv   +3 more sources

Neurogenesis Drives Stimulus Decorrelation in a Model of the Olfactory Bulb [PDF]

, 2012
The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory system? Using a computational network model for the dominant neural populations of the olfactory bulb we show that ...
A Arevian, A Fantana, A Mouret, A Mouret, A Sahay, AM McNamara, B Johnson, B Winner, Boris S. Gutkin, C Linster, C Rochefort, CW Lin, D Chaudhury, D Rinberg, D Wilson, DA Wilson, DJ Heeger, E Yaksi, F David, F Kermen, F Lazarini, F Lazarini, GA Cecchi, GK Mak, GK Mak, GM Shepherd, Hermann Riecke, I Imayoshi, I Ortega-Perez, J Ninkovic, JT Davie, L Belnoue, L Petreanu, LM Kay, M Alonso, M Satou, M Valley, M Whitman, M Yamaguchi, MC Whitman, MD Döbrössy, MM Moreno, MT Wiechert, N Kaneko, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Miwa, O Escanilla, P Panzanelli, PA Brennan, PE Castillo, PM Lledo, Q Nai, R Pressler, RE Dolmetsch, RW Friedrich, RW Friedrich, S Sultan, S Sultan, S Sultan, S Wick, Siu-Fai Chow, SR Olsen, SS Magavi, Stuart D. Wick, SW Kuffler, SX Luo, T Shingo, TA Cleland, TA Cleland, TB Woolf, TK Yokoyama, V Breton-Provencher, V Egger, V Egger, W Kelsch, W Kim, Y Gao   +81 more
arxiv   +8 more sources

Appetite for Neurogenesis [PDF]

Developmental Cell, 2017
Adult neural stem cells (NSCs) in the ventricular-subventricular zone (V-SVZ) produce diverse olfactory bulb (OB) neurons. In a recent paper in Science, Paul et al. (2017) show that hypothalamic propiomelanocortin (POMC) neurons innervate the anterior ventral V-SVZ and regulate deep granule interneuron production depending on feeding behavior.
Kristen L. Zuloaga, Sally Temple
openaire   +3 more sources

H3K36 Methylation in Neural Development and Associated Diseases

Frontiers in Genetics, 2020
Post-translational methylation of H3 lysine 36 (H3K36) is an important epigenetic marker that majorly contributes to the functionality of the chromatin.
Mattia Zaghi, Vania Broccoli, Vania Broccoli, Alessandro Sessa   +3 more
doaj   +1 more source

Neurogenesis and Epilepsy [PDF]

Epilepsia, 2010
Abstract Medial temporal lobe epilepsy (mTLE) is a common and often intractable form of epilepsy. Approximately 50 million people suffer from different epilepsies worldwide,1 30%–40% of whom may continue to have poorly controlled seizures despite therapy.2,3 Medial TLE is estimated to be the most common cause of intractable epilepsy in ...
Parent, Jack M., Kron, Michelle M.
openaire   +4 more sources

Modeling Reveals the Dependence of Hippocampal Neurogenesis Radiosensitivity on Age and Strain of Rats [PDF]

, 2018
Cognitive dysfunction following radiation treatment for brain cancers in both children and adults have been correlated to impairment of neurogenesis in the hippocampal dentate gyrus.
Cacao, Eliedonna, Cucinotta, Francis A., Kapukotuwa, Sidath   +2 more
core   +3 more sources