Results 11 to 20 of about 14,954 (288)
Purinoceptors on Neuroglia [PDF]
Molecular Neurobiology, 2009 Purinergic transmission is one of the most ancient and widespread extracellular signalling systems. In the brain, purinergic signalling plays a unique role in integrating neuronal and glial cellular circuits, as virtually every type of glial cell possesses receptors to purines and pyrimidines.
Alexei Verkhratsky +2 more
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Soursop leaf extract increases neuroglia and hepatic degeneration in female rats [PDF]
Universa Medicina, 2015 Background Soursop leaf contains annonaceous acetogenins and alkaloids. The acetogenins act as inhibitors of mitochondrial complex I, suppress ATP production and cause cell degeneration, whereas the alkaloids act as neurotoxins.
Ety Sari Handayani +3 more
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IBRO Reports, 2020 The technical difficulty to isolate microglia, astrocytes and infiltrating immune cells from mouse brain is nowadays a limiting factor in the study of neuroinflammation.
Belén Calvo +3 more
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Pathophysiology of Lipid Droplets in Neuroglia
Antioxidants, 2021 In recent years, increasing evidence regarding the functional importance of lipid droplets (LDs), cytoplasmic storage organelles in the central nervous system (CNS), has emerged.
Tina Smolič, Robert Zorec, Nina Vardjan
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Toxics, 2022 Evidence is now growing that exposure to environmental pollutants during the critical early-life period of brain development may contribute to the emergence of Autism Spectrum Disorders (ASD).
Chloé Morel +6 more
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Frontiers in Molecular Neuroscience, 2022 Huntington’s disease (HD) is an inherited autosomal dominant neurodegenerative disorder that leads to progressive motor and cognitive impairment. There are currently no available disease modifying treatments for HD patients. We have previously shown that
Si Han Li +8 more
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, 2019 As the nervous system evolved from the diffused to centralised form, the neurones were joined by the appearance of the supportive cells, the neuroglia. Arguably, these non-neuronal cells evolve into a more diversified cell family than the neurones are. The first ancestral neuroglia appeared in flatworms being mesenchymal in origin.
Verkhratsky, Alexei +2 more
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, 2019 Ageing reduces the functional capacity of all organs, so does that of the nervous system; the latter is evident in the reduction of cognitive abilities, learning and memory. While the exact mechanisms of ageing of the nervous system remain elusive, it is without doubt that morpho-functional changes in a variety of neuroglial cells contribute to this ...
Verkhratsky, Alexei +3 more
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Frontiers in Integrative Neuroscience, 2017 As part of the extracellular matrix (ECM), perineuronal nets (PNs) are polyanionic, chondroitin sulfate proteoglycan (CSPG)-rich coatings of certain neurons, known to be affected in various neural diseases.
Wolfgang Härtig +11 more
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