Results 101 to 110 of about 25,871 (216)
Cochlear Implantation in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease
ABSTRACT Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is a neuroimmunologic demyelinating disorder that may present with central or peripheral sensorineural hearing loss (SNHL). This case describes a 43‐year‐old female with MOGAD and profound right‐sided SNHL who did not improve with neuroimmunologic therapy.
Jacob Mabey +2 more
wiley +1 more source
On tumour‐reactive CD8+ TILs, CD39 drives two opposing fates at once: It marks cells actively cytolysing tumour cells via released ATP, yet also degrades that same ATP into adenosine, triggering A2AR signalling that locks the cells into a hypoxia‐amplified, self‐reinforcing immunosuppressive loop, blunting their own anti‐tumour action.
Manolo Sambucci +7 more
wiley +1 more source
11th International Congress of Neuroimmunology (ISNI) -- NOV 04-08, 2012 -- Boston, MAWOS: 000312764800046…European Sch Neuroimmunol, Int Soc Neuroimmunol ...
Vural, Burcak +6 more
core
Neuroimmunology of Stress: Skin Takes Center Stage [PDF]
Like few other organs, the skin is continuously exposed to multiple exogenous and endogenous stressors. Superimposed on this is the impact of psychological stress on skin physiology and pathology.
Theoharides, Theoharis C. +12 more
core +1 more source
Our data suggest that MBP interacts with astroglial cells, priming their activation, as proven by HLA class II modulation and HO-1 induction. MBP binding seems to be mediated by LRP,an endocytosis-mediating receptor.
BUSINARO R. +3 more
core
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley +1 more source
Rethinking the Oligodendrocyte Progenitor Cell: One Cell, Many Functions
Oligodendrocyte progenitor cells (OPCs) are increasingly recognised as multifunctional CNS cells rather than mere precursors of myelinating oligodendrocytes. Alongside myelination and remyelination, they contribute to myelin and circuit plasticity, circuit regulation, vascular and blood–brain barrier regulation and neuroimmune modulation.
Alerie G. de la Fuente
wiley +1 more source
Mast Cells in Host Defense Against Cutaneous Staphylococcus aureus Infection
Impact of S. aureus epicutaneous sensitization models on mast cell function in vivo. D. farinae and Staphylococcal enterotoxin B (SEB) activate Trpv1+ Tac1+ nociceptors to trigger the release of substance P (SP), which promotes mast cell degranulation through Mrgprb2. S.
Hannah Dychtenberg +3 more
wiley +1 more source
ABSTRACT Cognitive behavioural therapy for insomnia (CBT‐I) is recommended as first‐line treatment for insomnia disorder. However, around 25% of the patients do not respond to the treatment, and only 40% achieve full remission. The current study investigates the therapeutic potential of light therapy as an add‐on to CBT‐I.
Sarah R. Schmid +9 more
wiley +1 more source
Patient-derived monoclonal antibodies as a precise molecular tool to understand the pathophysiology of Caspr2-antibody encephalitis [PDF]
Caspr2-antibody encephalitis is a rare yet potentially treatable neurological disorder driven by autoimmunity against the neuronal cell adhesion molecule Caspr2.
Paneva, Sofija
core +1 more source

