Results 11 to 20 of about 440 (147)
Folia Medica Indonesiana, 2017 Rheumatoid arthritis (RA) is a chronic form of persistent inflammation. Meanwhile, Substance P is the most associated neuropeptide in neurogenic inflammation and hyperalgesia commonly found in chronic pain.
Yuyun Wirasasmita +3 more
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Frontiers in Molecular Neuroscience, 2023 The tachykinin hemokinin-1 (HK-1) is involved in immunological processes, inflammation, and pain. Although the neurokinin 1 receptor (NK1R) is described as its main target, several effects are mediated by currently unidentified receptor(s).
Krisztina Takács-Lovász +16 more
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Neurokinin-1 Receptor Blockade and Murine Lung Tumorigenesis [PDF]
American Journal of Respiratory and Critical Care Medicine, 2006 Abstract Rationale Analogous to the adenoma-carcinoma sequence in the colon, it has been proposed that adenocarcinoma (AC) in the lung arises from adenomatous hyperplasia that progresses through atypical adenomatous hyperplasia to AC.
LUCATTELLI, M. +4 more
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Romanian Medical Journal, 2021 Hot flashes (HF), transitory episodes of erythema, heat sensation, anxiety followed by chills, are described in carcinoid syndrome, mastocytosis, medullary thyroid cancer, hyperthyroidism, pheochromocytoma, alcohol consumption, side effects of drugs, and
Florica Sandru +7 more
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The Contribution of Phospholipase C in Vomiting in the Least Shrew (Cryptotis Parva) Model of Emesis
Frontiers in Pharmacology, 2021 Gq and Gβγ protein-dependent phospholipase C (PLC) activation is extensively involved in G protein-coupled receptor (GPCR)-mediated signaling pathways which are implicated in a wide range of physiological and pathological events.
Weixia Zhong, Nissar A. Darmani
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Substance P selectively decreases paired pulse depression in the rat hippocampal slice
BMC Neuroscience, 2005 Background Although being widespread in the hippocampus, the role tachykinins play in synaptic transmission is unclear. The effect of substance P on field potentials evoked by stimulation of the Schaffer collateral-commissural fibres and recorded from ...
Davies Stephen N, Wease Kerrie N
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Neurokinin-1 receptor signalling impacts bone marrow repopulation efficiency. [PDF]
PLoS ONE, 2013 Tachykinins are a large group of neuropeptides with both central and peripheral activity. Despite the increasing number of studies reporting a growth supportive effect of tachykinin peptides in various in vitro stem cell systems, it remains unclear ...
Alexandra Berger +8 more
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Cell Reports, 2020 Summary: Efficient Ca2+ flux induced during cognate T cell activation requires signaling the T cell receptor (TCR) and unidentified G-protein-coupled receptors (GPCRs).
Adrian E. Morelli +12 more
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European Journal of Histochemistry, 2023 Neurokinin-1 receptor (NK1R) belongs to tachykinin receptor family. Recent studies have suggested that NK1R was upregulated in cancer tissues including breast cancer, glioma and melanoma.
Liyun Guan +5 more
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Therapeutic Advances in Respiratory Disease, 2009 Objective: We previously reported that the nonpeptide tachykinin NK 2 receptor antagonist SR48968 (saredutant) significantly inhibits neurokinin A-induced bronchoconstriction in patients with asthma. MEN11420 (nepadutant) is a bicyclic peptide tachykinin
Venessa Schelfhout +4 more
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