Results 81 to 90 of about 12,085 (139)

Cellular metabolism of substance P produces neurokinin-1 receptor peptide agonists with diminished cyclic AMP signaling.

open access: yesAm J Physiol Cell Physiol
Kriska T   +8 more
europepmc   +1 more source

Dexamethasone-sparing on days 2-4 with combined palonosetron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial). [PDF]

open access: yesBr J Cancer
Minatogawa H   +29 more
europepmc   +1 more source

Neurokinin-1 receptors on the afferents to the raphe

open access: yes, 2016
Hafizi, S   +4 more
openaire   +2 more sources

Electroacupuncture on Baihui (DU20) and Xuehai (SP10) acupoints alleviates psoriatic inflammation by regulating neurotransmitter substance P- Neurokinin-1 receptor signaling. [PDF]

open access: yesJ Tradit Complement Med
Qi C   +13 more
europepmc   +1 more source

Safety of neurokinin-1 receptor antagonists

Expert Opinion on Drug Safety, 2013
The substance P (SP)/neurokinin (NK)-1 receptor system is involved in many pathological processes. NK-1 receptor antagonists have many promising therapeutic indications. However, the only NK-1 receptor antagonist used in clinical practice is the drug aprepitant and its intravenously administered prodrug, fosaprepitant.
Miguel, Muñoz, Rafael, Coveñas
openaire   +2 more sources

Neurokinin-1 Receptor Resensitization Precedes Receptor Recycling

The Journal of Pharmacology and Experimental Therapeutics, 2005
Following agonist binding, neurokinin-1 receptors undergo rapid desensitization followed by internalization and recycling. Desensitization requires receptor phosphorylation but does not require internalization, whereas resensitization is thought to require internalization and recycling.
V J, Bennett, S A, Perrine, M A, Simmons
openaire   +2 more sources

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