Results 91 to 100 of about 119,703,502 (227)

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Chemotherapy‐Induced Nausea and Vomiting in Early Breast Cancer Patients Receiving Adjuvant Chemotherapy With Fluorouracil, Epirubicin, Cyclophosphamide Followed by Docetaxel Versus an Anthracycline‐Free Regimen With Docetaxel, Cyclophosphamide—Results From a Randomized Clinical Trial

International Journal of Cancer, Volume 159, Issue 8, Page 1990-2003, 15 October 2026.
Chemotherapy‐induced nausea and vomiting (CINV) remains a significant clinical problem despite modern antiemetics. In particular, antiemetic strategies for emerging cancer therapies lack detailed evaluation. This randomized trial analyzed hourly CINV data for patients with early breast cancer who received either docetaxel plus cyclophosphamide (TC) or ...
Manuel Hörner, Henning Schäffler, Lothar Häberle, Chloë Goossens, Kerstin Pfister, Elena Leinert, Kristina Veselinovic, Sara Y. Brucker, Uwe Köhler, Georg Heinrich, Andreas Schneeweiss, Matthias W. Beckmann, Peter A. Fasching, Wolfgang Janni, Brigitte Rack, Sabine Heublein, Philipp Ziegler   +16 more
wiley   +1 more source

Effect of inhaled substance P and neurokinin A on the airways of normal and asthmatic subjects [PDF]

, 1987
The neuropeptides substance P and neurokinin A are present in sensory airway nerves. Their effect on airway calibre was compared in six healthy non-smoking subjects and six asthmatic subjects. On separate days increasing concentrations (from 10(-9) to 10(
Joos, Guy, Van Der Straeten, Marcel E, Pauwels, Romain   +2 more
core   +1 more source

Malnutrition alters protein expression of KNDy neuropeptides in the arcuate nucleus of mature ewes

Frontiers in Physiology
The neuropeptides kisspeptin, neurokinin B, and dynorphin A are imperative for the pulsatile secretion of gonadotropin-releasing hormone and luteinizing hormone to ultimately regulate reproductive cyclicity.
Jennifer F. Thorson, Ligia D. Prezotto
doaj   +1 more source

Actions of tachykinins on the rabbit mesenteric artery: substance P and [Glp6,L-Pro9]SP6-11 are potent agonists for endothelial neurokinin-1 receptors

, 1989
1. Identification of the subtype of neurokinin receptor on the endothelium of the rabbit mesenteric artery was demonstrated by comparing the relative potencies of the naturally occurring tachykinins, substance P, neurokinin A and neurokinin B and the ...
Geoffrey Burnstock, Burnstock, G., Stewart-Lee, A.; id_orcid, Anne Stewart-Lee   +3 more
core   +1 more source

Development of Novel Neurokinin 3 Receptor (NK3R) Selective Agonists with Resistance to Proteolytic Degradation

, 2016
Neurokinin B (NKB) regulates the release of gonadotropin-releasing hormone (GnRH) via activation of the neurokinin-3 receptor (NK3R). We evaluated the biological stability of NK3R selective agonists to develop novel NK3R agonists to regulate reproductive
Hiroaki Ohno (1457971), Hiroaki Okamura (486408), Shinya Oishi (164565), Ai Yamada (1730698), Fuko Matsuda (1730704), Nobutaka Fujii (164590), Takashi Yamamura (20115), Ryosuke Misu (1667896), Koki Yamamoto (1730701), Taro Noguchi (698875), Satoshi Ohkura (1730695)   +10 more
core   +1 more source

Vasopressin release induced by intracranial injection of tachykinins is due to activation of central neurokinin-3 receptors.

, 1989
The present study investigated the effect on vasopressin release of the intracerebroventricular injection of tachykinins in rats. The selective neurokinin (NK)-3 receptor agonists [MePhe7]neurokinin B and [Asp5,6MePhe8]substance P(5-11) evoked ...
POLIDORI, Carlo, PERFUMI, Marina Cecilia, Saija A, de Caro G, MASSI, Maurizio, Costa G   +5 more
core   +2 more sources

Histamine release from human bronchoalveolar lavage mast cells by neurokinin A and bradykinin

, 1997
Objective and Design: This study examined whether bradykinin and neurokinin A activate human pulmonary mast cells retrieved by bronchoalveolar lavage (BAL)
Ennis, Madeleine, Cross, L.J.M., Heaney, Liam   +2 more
core   +2 more sources

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

Neurokinin b signalling in human puberty

, 2010
PubMedID: 20456599Recent identification of TAC3 or TACR3 (encoding neurokinin B and its receptor, NK3R, respectively) mutations as the causes of normosmic idiopathic hypogonadotrophic hypogonadism has provided compelling evidence for the involvement of ...
Yuksel B., Topaloglu A.K., Kotan L.D., A. Kemal Topaloglu, L. Damla Kotan, Bilgin Yuksel   +5 more
core   +1 more source