Results 71 to 80 of about 92,938,436 (228)

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Will elinzanetant, a neurokinin receptor antagonist, have a role in the treatment of hot flashes?

Introduction The use of hormonal treatment for the vasomotor symptoms (VSM) associated with the menopause is back in favor, as the adverse effects reported in the early 2000s have been dispelled.
Doggrell, Sheila A
core   +1 more source

Neurokinin B levels in maternal circulation during early pregnancy

, 2004
Neurokinin B levels were measured between the 10th-20th weeks of pregnancy, i.e., prior to the development of clinical symptoms, in women who developed preeclampsia or delivered a growth-restricted baby.
Tjoa, May Lee, Oudejans, Cees B M, van Wijk, Inge J, Blankenstein, Marinus A, Lomecky, Marie, van Vugt, John M G, Martens, Frans   +6 more
core   +1 more source

Involvement of Substance P and the Neurokinin-1 Receptor in Radiation-Induced Hair Loss in Mice

Journal of Pharmacological Sciences, 2010
We investigated the involvement of substance P (SP) and the neurokinin-1 receptor (NK1 R) in the development of radiation-induced hair loss in mice.
Kouichi Yamamoto, Naoko Kureyama, Keiko Asano, Toshiji Ikeda, Atsushi Yamatodani   +4 more
doaj   +1 more source

Effects of photobiomodulation therapy on pulmonary inflammation in chronic asthma: Dosimetric study in an experimental model

Photochemistry and Photobiology, EarlyView.
Photobiomodulation therapy (PBMT) was evaluated across a radiant energy range (1–7.5 J) in a murine model of chronic ovalbumin‐induced asthma to identify the optimal therapeutic dose. PBMT attenuated airway inflammation and remodelling, suppressed Th2 cytokines, and enhanced regulatory immune responses, highlighting a dose‐dependent immunomodulatory ...
Tawany Gonçalves Santos, Cintia Estefano Alves, Aurileia Aparecida de Brito, Bibiana Padilha de Menezes da Silva, Cinthya Cosme Gutierrez Duran, Stella Zamuner, Rodrigo Labat, José Antonio Silva Junior, Maria Cristina Chavantes, Flavio Aimbire, Renata Kelly da Palma, Ana Paula Ligeiro de Oliveira   +11 more
wiley   +1 more source

cDNA sequence of human β-preprotachykinin, the common precursor to substance P and neurokinin A [PDF]

, 1986
The nucleotide sequence of cDNA encoding the human substance P precursor, β-preprotachykinin (β-PPT), has been determined. The source of mRNA was a human laryngeal carcinoid tumour that contained a high concentration of immunoreactive substance P.
A. Armstrong, G. Fink, A.J. Harmar, Rosie, R., A. Curtis, Edwards, C.R.W., Harmar, A.J., Pascall, J.C., Chapman, K., Curtis, A., Going, J., K. Chapman, J. Going, Fink, G., J.C. Pascall, Armstrong, A., C.R.W. Edwards, R. Rosie   +17 more
core   +1 more source

Microvascular endothelial function is blunted in postmenopausal females with frequent hot flushes

Experimental Physiology, EarlyView.
Abstract Hot flushes of menopause are associated with elevated blood pressure (BP) and diminished macrovascular endothelial function, an initiating factor in the onset of atherosclerosis. Whether microvascular endothelial function is impaired in females with hot flushes, however, remains unknown.
William Stokes, Chowdhury Tasnova Tahsin, Miguel F. Anselmo, Stephany Nathe, Emma J. Lee, Soliana Teshome, Marnie L. Vanden Noven, Anne Blaes, Benjamin W. Langworthy, Manda L. Keller‐Ross   +9 more
wiley   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Mapping of neurokinin b in the cat brainstem [PDF]

, 2020
We studied the distribution of neurokinin B-immunoreactive cell bodies and fibers in the cat brainstem using an indirect immunoperoxidase technique. The highest density of immunoreactive fibers was found in the motor trigeminal nucleus, the laminar and ...
Ae J A Narvaez, L A Aguilar, J Rioja, I Cuadrado, Sabio, Incyl, Ae R Coven˜as, Alfonso X El, Ae J Rioja, Ae J A Aguirre, Anat Embryol, J A Aguirre, Ae L A Aguilar   +12 more
core  

Serum Spexin, Kisspeptin-1, Substance P, and Neurokinin-1 Receptor Levels in Hyperemesis Gravidarum: A Prospective Paired Follow-Up Study

Cumhuriyet Science Journal
Hyperemesis gravidarum (HG) is characterized by severe nausea and vomiting during pregnancy and may adversely affect both maternal health and fetal development.
Ayça Taş, Dilay Karademir, Tugba Agbektas, Zuhal Tunçbilek, Gülcihan Cinar Kaya, Yavuz Siliğ   +5 more
doaj   +1 more source