Results 61 to 70 of about 489,270 (329)

Neuronosology: historical remarks

open access: yesArquivos de Neuro-Psiquiatria, 2011
Classifications for neurological disorders have evolved from following the theory of the humors to modern anatomical pathology and, recently, to the germ theory that stared the etiological era, as seen in book content lists.
Marleide da Mota Gomes
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Microbial risk factors of cardiovascular and cerebrovascular diseases: potential therapeutic options [PDF]

open access: yes, 2008
Infection and inflammation may have a crucial role in the pathogenesis of atherosclerosis. This hypothesis is supported by an increasing number of reports on the interaction between chronic infection, inflammation, and atherogenesis.
Abbas, M.A.   +6 more
core   +1 more source

PERSPECTIVES OF THERAPY WITH CEREBROLYSIN IN NEUROLOGY AND ITS PLACE IN CLINICAL PRACTICE OF PEDIATRIC NEUROLOGY

open access: yesРусский журнал детской неврологии, 2015
A detailed review of the literature, reflecting many aspects of сerebrolysin in a wide range of nervous system disorders, including various diseases in children is described.
A. S. Petrukhin, O. A. Pylaeva
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Differential expression profiles of lncRNAs and a preliminary study on the mechanism of lncRNA FAM225A in triple seronegative myasthenia gravis

open access: yesFrontiers in Immunology
BackgroundTriple-seronegative (Triple-SN) myasthenia gravis (MG) is a subtype of MG, and its diagnosis and treatment are challenging. Our study aims to discover new biomarkers and potential therapeutic targets and explore the preliminary mechanisms of ...
Yuehan Hao   +13 more
doaj   +1 more source

Publication trends of neurology articles in a biomedical journal from India

open access: yesAnnals of Indian Academy of Neurology, 2012
Background: The details about the research productivity in the neurology specialty from India is lacking. We analyzed the publishing trends and the research productivity of neurology-related articles in the Journal of the Association of Physicians of ...
K. V. S. Hari Kumar, K Aravinda
doaj   +1 more source

Doxycycline Induces Apoptosis of Brucella Suis S2 Strain-Infected HMC3 Microglial Cells by Activating Calreticulin-Dependent JNK/p53 Signaling Pathway

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Neurobrucellosis is a chronic complication of human brucellosis that is caused by the presence of Brucella spp in the central nervous system (CNS) and the inflammation play a key role on the pathogenesis.
Zhao Wang   +5 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Ontologies for the study of neurological disease [PDF]

open access: yes, 2012
We have begun work on two separate but related ontologies for the study of neurological diseases. The first, the Neurological Disease Ontology (ND), is intended to provide a set of controlled, logically connected classes to describe the range of ...
Cox, Alexander P.   +7 more
core  

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